ArticleKidney international reports2021
Cardiac Outcomes in Isolated Heart and Simultaneous Kidney and Heart Transplants in the United States.
Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Simultaneous Heart and Kidney Transplantation: A Systematic Review and Proportional Meta-Analysis of Its Characteristics and Long-Term Variables.Transplant international : official journal of the European Society for Organ Transplantation · 2024Pooled it
- Higher model for end-stage liver disease excluding international normalized ratio scores predict worse kidney graft outcomes in simultaneous heart-kidney transplantation.World journal of transplantation · 2026Article
- A Paired Kidney Analysis of Simultaneous Heart-Kidney Transplantation and Kidney Transplantation After Heart Transplantation.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025Article
- Understanding the role of temporary epicardial pacemakers after heart transplantation in the cardiac intensive care unit.JHLT open · 2024Article
- Management of patients with heart failure and chronic kidney disease.Heart failure reviews · 2024Review
- Evolutions in Combined Heart-Kidney Transplant.Current heart failure reports · 2024Review
- Simultaneous heart-kidney transplant in patients with borderline estimated glomerular filtration rate without dialysis dependency.Clinical transplantation · 2023Article
- Value of Renal Histology in Predicting Cardiorenal Outcomes in Heart Transplant-listed Patients.Transplantation direct · 2023Article
- Current considerations for heart-kidney transplantation.Frontiers in transplantation · 2022Review
- Letter Regarding "Cardiac Outcomes in Isolated Heart and Simultaneous Kidney and Heart Transplants in the United States".Kidney international reports · 2022Article
- In Reply to "Letter Regarding 'Cardiac Outcomes in Isolated Heart and Simultaneous Kidney and Heart Transplants in the United States'".Kidney international reports · 2022Article
- Combined Heart-Kidney Transplantation: Indications, Outcomes, and Controversies.Methodist DeBakey cardiovascular journal · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionKidney dysfunction is not uncommon in patients with advanced heart failure. Simultaneous kidney and heart transplants (SKHTs) have gained acceptance as a treatment for patients with end-stage heart failure and severe kidney dysfunction. United States saw a rise of 650% in SKHT from 2000 to 2019. Despite increasing number of SKHT, the selection criteria remain poorly defined and vary across transplant centers.
methodsWe evaluated patient and cardiac allograft survival for SKHT and heart transplant alone (HTA) using the United Network for Organ Sharing (UNOS) database. We then performed a subgroup analysis in recipients with post-transplant acute kidney injury requiring renal replacement therapy (RRT) and compared outcomes between SKHT and HTA recipients.
resultsAlthough patient survival was comparable between SKHT and HTA groups (12.4 vs. 11.3 years), patients dependent on dialysis pretransplant derived greater survival advantage from SKHT as compared with HTA (12.4 vs. 9.9 years). Cardiac graft survival was better in SKHT (12.5 vs. 11.2 years). Among patients who developed acute kidney injury requiring RRT postoperatively, SKHT recipients had a significantly better survival (11.9 vs. 2.7 years).
conclusionOur data support consideration of SKHT in dialysis-dependent heart transplant candidates and suggest that patients who are at increased risk of requiring RRT after heart transplant may benefit from SKHT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.