Evidence map›Paper›PMID 34514110›Full record

ArticleTransplantation direct2021

Clinical Practice Guideline for Solid Organ Donation and Transplantation During the COVID-19 Pandemic.

Matthew J Weiss, Laura Hornby, Farid Foroutan, Sara Belga, Simon Bernier, Mamatha Bhat, C Arianne Buchan, Michael Gagnon, Gillian Hardman, Maria Ibrahim and 14 more

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Issues regarding COVID-19 in kidney transplantation in the ERA of the Omicron variant: a commentary by the ERA Descartes Working Group.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022
    Article
  8. Article
  9. [Long-term physical and psychological consequences of chronic kidney disease].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 11 institutions in 2 countries.

Matthew J WeissTransplant Québec, Montréal, QC, Canada.
Laura HornbyCanadian Donation and Transplantation Research Program (CDTRP), Ottawa, ON, Canada.
Farid ForoutanDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Sara BelgaDivision of Infectious Diseases, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Simon BernierFaculty of Medicine, Université Laval, QC, Canada.
Mamatha BhatDivision of Gastroenterology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
C Arianne BuchanDivision of Infectious Diseases, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
Michael GagnonDivision of Nephrology and Multi-Organ Transplant Program, Department of Medicine, McGill University, Montreal, QC, Canada.
Gillian HardmanNational Health Service Blood and Transplant, Bristol, United Kingdom.
Maria IbrahimNational Health Service Blood and Transplant, Bristol, United Kingdom.
Cindy LuoFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.
Me-Linh LuongDepartment of Microbiology, Infectiology and Immunology, Université de Montréal, Montréal, QC, Canada.
Rahul MainraDivision of Nephrology, University of Saskatchewan, Saskatoon, SK, Canada.
Alex R ManaraNational Health Service Blood and Transplant, Bristol, United Kingdom.
Ruth Sapir-PichhadzeDivision of Nephrology and Multi-Organ Transplant Program, Department of Medicine, McGill University, Montreal, QC, Canada.
Sarah ShalhoubDivision of Infectious Diseases, Department of Medicine, Western University, London, ON, Canada.
Tina ShaverSouthern Alberta Organ and Tissue Donation Program, Calgary, AB, Canada.
Jeffrey M SinghDepartment of Medicine, University of Toronto, Toronto, Ontario, ON, Canada.
Sujitha SrinathanDivision of Gastroenterology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Ian ThomasNational Health Service Blood and Transplant, Bristol, United Kingdom.
Lindsay C WilsonSystem Development - Organ and Tissue Donation and Transplantation, Canadian Blood Services, Ottawa, ON, Canada.
T Murray WilsonTransplant Research Foundation of British Columbia, Vancouver, BC, Canada.
Alissa WrightDivision of Infectious Diseases, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Allison MahDivision of Infectious Diseases, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
University of British Columbia · CAUniversity of Toronto · CATranslational Research in Oncology · CAMcGill University · CAImpact · CAKing's College London · GBNational Health Service · GBUniversité de Montréal · CAUniversity of Ottawa · CAUniversity of Saskatchewan · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus 2019 (COVID-19) pandemic has disrupted health systems worldwide, including solid organ donation and transplantation programs. Guidance on how best to screen patients who are potential organ donors to minimize the risks of COVID-19 as well as how best to manage immunosuppression and reduce the risk of COVID-19 and manage infection in solid organ transplant recipients (SOTr) is needed.

methodsIterative literature searches were conducted, the last being January 2021, by a team of 3 information specialists. Stakeholders representing key groups undertook the systematic reviews and generation of recommendations using a rapid response approach that respected the Appraisal of Guidelines for Research and Evaluation II and Grading of Recommendations, Assessment, Development and Evaluations frameworks.

resultsThe systematic reviews addressed multiple questions of interest. In this guidance document, we make 4 strong recommendations, 7 weak recommendations, 3 good practice statements, and 3 statements of "no recommendation."

conclusionsSOTr and patients on the waitlist are populations of interest in the COVID-19 pandemic. Currently, there is a paucity of high-quality evidence to guide decisions around deceased donation assessments and the management of SOTr and waitlist patients. Inclusion of these populations in clinical trials of therapeutic interventions, including vaccine candidates, is essential to guide best practices.

Identifiers

PMID34514110
PMCPMC8425831
OpenAlexW3198015964

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.