Evidence map›Paper›PMID 34514079›Full record

ArticleInformatics in medicine unlocked2021

Identification of novel transmembrane Protease Serine Type 2 drug candidates for COVID-19 using computational studies.

Fatima A Elbadwi, Elaf A Khairy, Fatima O Alsamani, Mariam A Mahadi, Segood E Abdalrahman, Zain Alsharf M Ahmed, Inas Elsayed, Walaa Ibraheem, Abdulrahim A Alzain

Open access · goldAbstract read
In one paragraph

Article in Informatics in medicine unlocked, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Discovery of novel TMPRSS2 inhibitors for COVID-19 usingInformatics in medicine unlocked · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Fatima A ElbadwiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Elaf A KhairyDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Fatima O AlsamaniDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Mariam A MahadiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Segood E AbdalrahmanDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Zain Alsharf M AhmedDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Inas ElsayedDepartment of Pharmacology, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Walaa IbraheemDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
Abdulrahim A AlzainDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Gezira, Gezira, Sudan.
University of Gezira · SD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emergence has resulted in a global health crisis. As a consequence, discovering an effective therapy that saves lives and slows the spread of the pandemic is a global concern currently.

Indexed as

COVID-19DockingDrug repurposingHomology modelingMolecular dynamicsTMPRSS2

Identifiers

PMID34514079
PMCPMC8421083
OpenAlexW3198915637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.