ArticleJournal of dentistry (Shiraz, Iran)2021
Evaluation of Salivary Level of Heat Shock Protein 70 in Patients with Chronic Periodontitis.
Article in Journal of dentistry (Shiraz, Iran), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Effects of initial periodontal treatment on heat shock protein 90 and Interleukin-1β levels in gingival crevicular fluid of stage III periodontitis patients.BMC oral health · 2025Article
- Saliva as a Diagnostic Tool for Systemic Diseases-A Narrative Review.Medicina (Kaunas, Lithuania) · 2025Review
- Changes in the components of salivary exosomes due to initial periodontal therapy.Journal of periodontal & implant science · 2023Article
- Article
- Label-Free Quantitative Proteomic Analysis Reveals Inflammatory Pattern Associated with Obesity and Periodontitis in Pregnant Women.Metabolites · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
statement of the problemTraditional clinical criteria are usually not sufficient for determining the sites of active periodontal disease, monitoring the response to treatment, or measuring the susceptibility to future disease development. Past studies have shown that heat shock protein 70 (HSP70) are involved in the etiology of periodontal disease. PURPOSE: The aim of this study was to evaluate the level of HSP70 in saliva of patients with chronic periodontitis (CP). MATERIALS AND
methodIn our case-control study, the saliva samples of 45 patients with CP and 45 age- and sex-matched healthy subjects were collected. Salivary HSP70 was measured by enzyme-linked immunosorbent assay method. The results were analyzed by statistical tests using SPSS 16 and the statistically significant difference was set at
resultsIn this study, the mean salivary HSP70 level was 2.81±0.61ng/ml in the patient group and 1.96±0.77ng/ml in the healthy group, with a significant difference (
conclusionThe results of this study showed that the salivary HSP70 level in patients with CP is higher than that in healthy subjects. As a result, salivary HSP70 might be considered as a marker in the pathogenesis of CP.
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