Evidence map›Paper›PMID 34514022›Full record

ArticleChild neurology open

Validating Coding for the Identification of Pediatric Treatment Resistant Epilepsy Patients.

Daniel A Freedman, Zachary Grinspan, Peter Glynn, Jackson Mittlesteadt, Alex Dawes, Anup D Patel

Abstract read
In one paragraph

Article in Child neurology open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel A FreedmanDell Medical School, The University of Texas at Austin, Austin, TX, USA.ORCID https://orcid.org/0000-0003-1340-0233
Zachary GrinspanWeill Cornell Medical Center, New York, NY, USA.
Peter GlynnNationwide Children's Hospital, Columbus, OH, USA.
Jackson MittlesteadtNationwide Children's Hospital, Columbus, OH, USA.
Alex DawesNationwide Children's Hospital, Columbus, OH, USA.
Anup D PatelNationwide Children's Hospital, Columbus, OH, USA.ORCID https://orcid.org/0000-0001-9313-1541

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The International Classification of Diseases (ICD) system includes sub codes to indicate that an individual with epilepsy is treatment resistant. These codes would be a valuable tool to identify individuals for quality improvement and population health, as well as for recruitment into clinical trials. However, the accuracy of these codes is unclear. We performed a single center cross sectional study to understand the accuracy of ICD codes for treatment resistant epilepsy. We identified 344 individuals, roughly half with treatment resistant epilepsy The ICD code had a sensitivity of 90% (147 of 164) and specificity of 86% (155 of 180). The miscoding of children with refractory epilepsy was attributed to the following reasons: 5 patients had epilepsy surgery, 4 had absence epilepsy, 4 patients were seen by different providers, and 1 patient was most recently seen in movement disorders clinic. ICD codes accurately identify children with treatment resistant epilepsy.

Indexed as

childrenepilepsypediatricrefractoryseizures

Identifiers

PMID34514022
PMCPMC8424723

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.