Evidence map›Paper›PMID 34514020›Full record

ArticleOpen forum infectious diseases2021

Serological and RT-PCR Surveillance for COVID-19 in an Asymptomatic US Army Trainee Population.

Shilpa Hakre, Aaron D Sanborn, Stephen W Krauss, Jennifer L Burns, Kenya N Jackson, Melanie D McCauley, Brittany L Ober Shepherd, Samantha McHenry, Shauna L Stahlman, Elizabeth J Bianchi and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Shilpa HakreEmerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Aaron D SanbornClinical Trials Center, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Stephen W KraussCenter for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Jennifer L BurnsDiagnostics and Countermeasures Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Kenya N JacksonExperimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Melanie D McCauleyEmerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Brittany L Ober ShepherdEmerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Samantha McHenryHenry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
Shauna L StahlmanArmed Forces Health Surveillance Division, Silver Spring, Maryland, USA.
Elizabeth J BianchiEmerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Joanna FreemanHenry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
Jason OuelletteHenry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
Jeremiah StubbsMoncrief Army Health Clinic, Fort Jackson, South Carolina, USA.
Crystal BriganttiMoncrief Army Health Clinic, Fort Jackson, South Carolina, USA.
Tara L HallMoncrief Army Health Clinic, Fort Jackson, South Carolina, USA.
Milford H BeagleUnited States Army Training Center, Fort Jackson, South Carolina, USA.
Paul O KwonMoncrief Army Health Clinic, Fort Jackson, South Carolina, USA.
Jason A PieriUnited States Army Training Center, Fort Jackson, South Carolina, USA.
Timothy R FrambesUnited States Army Training Center, Fort Jackson, South Carolina, USA.
Clinton K MurrayWalter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Steven B CersovskyUS Army Public Health Center, Aberdeen Proving Ground, Maryland, USA.
Kayvon ModjarradEmerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Sheila A PeelDiagnostics and Countermeasures Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Paul T ScottEmerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSignificant variability exists in the application of infection control policy throughout the US Army initial entry training environment. To generate actionable information for the prevention of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/coronavirus disease 2019 (COVID-19) transmission among new recruits, active enhanced surveillance was conducted for evidence of and exposure to SARS-CoV-2/COVID-19.

methodsWe serially tested recruits with a reverse transcriptase polymerase chain reaction (RT-PCR) COVID-19 and/or total antibody to SARS-CoV-2 tests at days 0, 14, and week 10 upon arrival for basic combat training at a location in the Southern United States.

resultsAmong 1403 recruits who were enrolled over a 6-week period from August 25 through October 11, 2020, 84 recruits tested positive by RT-PCR, with more than half (55%, 46/84) testing positive at arrival and almost two-thirds (63%, 53/84) also testing seropositive at arrival. Similarly, among an overall 146 recruits who tested seropositive for SARS-CoV-2 during the period of observation, a majority (86%) tested seropositive at arrival; no hospitalizations were observed among seropositive recruits, and antibody response increased at week 10.

conclusionsThese findings that suggest serological testing may complement current test-based measures and provide another tool to incorporate in COVID-19 mitigation measures among trainees in the US Army.

Indexed as

ArmyasymptomaticCOVID-19recruitserology

Identifiers

PMID34514020
PMCPMC8418190

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.