Evidence map›Paper›PMID 34514003›Full record

ReviewJournal of immunology research2021

Tumor Biomarker In-Solution Quantification, Standard Production, and Multiplex Detection.

Nicole C Japp, Joshua J Souchek, Aaron R Sasson, Michael A Hollingsworth, Surinder K Batra, Wade M Junker

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Editorial: New progress in cancer biomarkers and therapy.Frontiers in molecular biosciences · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nicole C JappSanguine Diagnostics and Therapeutics, Inc., Omaha, Nebraska, USA.
Joshua J SouchekSanguine Diagnostics and Therapeutics, Inc., Omaha, Nebraska, USA.
Aaron R SassonSanguine Diagnostics and Therapeutics, Inc., Omaha, Nebraska, USA.
Michael A HollingsworthSanguine Diagnostics and Therapeutics, Inc., Omaha, Nebraska, USA.
Surinder K BatraSanguine Diagnostics and Therapeutics, Inc., Omaha, Nebraska, USA.
Wade M JunkerSanguine Diagnostics and Therapeutics, Inc., Omaha, Nebraska, USA.ORCID https://orcid.org/0000-0002-2649-3996
University of Nebraska Medical Center · USStony Brook School · US

Funding

MUC4/16 assay for the early diagnosis and management of benign and malignant pancreatic diseasesR44DK117472 · NIDDK · SANGUINE DIAGNOSTICS AND THERAPEUTICS · PI JAIN, MANEESH, SASSON, AARON R · 2017 to 2019
$1.5M
Seromic Mucin Signature for the Early Diagnosis of Pancreatic CancerR44CA224619 · NCI · SANGUINE DIAGNOSTICS AND THERAPEUTICS · PI JAIN, MANEESH, SOUCHEK, JOSHUA JAMES · 2018 to 2019
$1.5M
Combinatorial Biomarkers for Malignant Polyps and Colon Cancer DetectionR43CA235984 · NCI · SANGUINE DIAGNOSTICS AND THERAPEUTICS · PI JAIN, MANEESH, JUNKER, WADE M · 2019 to 2019
$225k
NCI NIH HHS R43 CA235984NCI NIH HHS R44 CA224619NIDDK NIH HHS R44 DK117472
6 · The paper itself

Abstract

The diagnosis and monitoring of cancer have been facilitated by discovering tumor "biomarkers" and methods to detect their presence. Yet, for certain cancers, we still lack sensitive and specific biomarkers or the means to quantify subtle concentration changes successfully. The identification of new biomarkers of disease and improving the sensitivity of detection will remain key to changing clinical outcomes. Patient liquid biopsies (serum and plasma) are the most easily obtained sources for noninvasive analysis of proteins that tumor cells release directly and via extracellular microvesicles and tumor shedding. Therefore, an emphasis on creating reliable assays using serum/plasma and "

Indexed as

Biomarkers, TumorAutomationColorimetryDisease ManagementEnzyme-Linked Immunosorbent AssayHumansLiquid BiopsyLuminescent MeasurementsNeoplasmsROC CurveSensitivity and SpecificityBiomarkers, Tumor

Identifiers

PMID34514003
PMCPMC8426080
OpenAlexW3196297782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.