Evidence map›Paper›PMID 34513976›Full record

ArticleFrontiers in veterinary science2021

Effect of the Inoculation Site of Bovine and Avian Purified Protein Derivatives (PPDs) on the Performance of the Intradermal Tuberculin Test in Goats From Tuberculosis-Free and Infected Herds.

Javier Ortega, Álvaro Roy, Julio Álvarez, José Sánchez-Cesteros, Beatriz Romero, Jose A Infantes-Lorenzo, José L Sáez, Marisol López, Lucas Domínguez, Lucia de Juan and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Javier OrtegaVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Álvaro RoyVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Julio ÁlvarezVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
José Sánchez-CesterosVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Beatriz RomeroVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Jose A Infantes-LorenzoServicio de Inmunología Microbiana, Centro Nacional de Microbiología, Instituto de Investigación Carlos III, Majadahonda, Spain.
José L SáezMinisterio de Agricultura, Pesca y Alimentación, Madrid, Spain.
Marisol LópezServicio Territorial de Agricultura, Ganadería y Desarrollo Rural de Ávila- Sección de Sanidad y Producción Animal, Ávila, Spain.
Lucas DomínguezVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Lucia de JuanVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Javier BezosVISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, Spain.
Universidad Complutense de Madrid · ESCatholic University of Ávila · ESCentro Nacional de Microbiologia · ESMinisterio de Agricultura, Pesca y Alimentación · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The single and comparative intradermal tuberculin (SIT and CIT) tests are used for the ante-mortem diagnosis of caprine tuberculosis (TB). The tuberculin injection site has been associated with a different performance of the test in cattle. In contrast to that required in cattle in Europe (cervical injection), it can be carried out in the scapular region in goats. Nevertheless, there are no previous data concerning the effect of the injection site on the performance of the test in goats. The aim of the present study was to evaluate the effect of two different inoculation sites (cervical and scapular) on the performance of the SIT/CIT tests. This was done by intradermally inoculating 309 goats from two infected herds and one TB-free herd with both avian and bovine PPDs in the mid-cervical and scapular regions. None of the animals from the TB-free herd had positive reactions, and the number of reactors was not significantly higher, regardless of the inoculation site, in the high and low prevalence herds. However, significantly higher increases in skin fold thickness were observed on the cervical site when compared to the scapular site after the avian and bovine PPD inoculations in the TB-free herd (

Indexed as

goatharmonizationinoculation siteintradermal teststuberculosis

Identifiers

PMID34513976
PMCPMC8429842
OpenAlexW3193870100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.