Evidence map›Paper›PMID 34513810›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Effect of Tension on Human Periodontal Ligament Cells: Systematic Review and Network Analysis.

Changyun Sun, Mila Janjic Rankovic, Matthias Folwaczny, Sven Otto, Andrea Wichelhaus, Uwe Baumert

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Epigenetic Connections in Malocclusion.International journal of molecular sciences · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Changyun SunDepartment of Orthodontics and Dentofacial Orthopedics, University Hospital, LMU Munich, Munich, Germany.
Mila Janjic RankovicDepartment of Orthodontics and Dentofacial Orthopedics, University Hospital, LMU Munich, Munich, Germany.
Matthias FolwacznyDepartment of Conservative Dentistry and Periodontology, University Hospital, LMU Munich, Munich, Germany.
Sven OttoDepartment of Oral and Maxillofacial Plastic Surgery, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Andrea WichelhausDepartment of Orthodontics and Dentofacial Orthopedics, University Hospital, LMU Munich, Munich, Germany.
Uwe BaumertDepartment of Orthodontics and Dentofacial Orthopedics, University Hospital, LMU Munich, Munich, Germany.
Ludwig-Maximilians-Universität München · DELMU Klinikum · DEMartin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthodontic tooth movement is based on the remodeling of tooth-surrounding tissues in response to mechanical stimuli. During this process, human periodontal ligament cells (hPDLCs) play a central role in mechanosensing and mechanotransduction. Various

Indexed as

mechanical stressorthodontic tooth movementperiodontal ligament fibroblaststensiontissue remodelling

Identifiers

PMID34513810
PMCPMC8429507
OpenAlexW3198489443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.