Evidence map›Paper›PMID 34513748›Full record

ArticleJournal of hepatocellular carcinoma2021

Deep Learning-Based Prediction of Future Extrahepatic Metastasis and Macrovascular Invasion in Hepatocellular Carcinoma.

Sirui Fu, Meiqing Pan, Jie Zhang, Hui Zhang, Zhenchao Tang, Yong Li, Wei Mu, Jianwen Huang, Di Dong, Chongyang Duan and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of hepatocellular carcinoma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
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  5. Technological Advancements in Interventional Oncology.Diagnostics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Sirui Fu *Zhuhai Interventional Medical Centre, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Zhuhai, People's Republic of China.
Meiqing Pan *Beijing Advanced Innovation Centre for Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, People's Republic of China.
Jie Zhang *Department of Radiology, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Zhuhai, People's Republic of China.
Hui Zhang *Beijing Advanced Innovation Centre for Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, People's Republic of China.
Zhenchao TangBeijing Advanced Innovation Centre for Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, People's Republic of China.
Yong LiZhuhai Interventional Medical Centre, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Zhuhai, People's Republic of China.
Wei MuBeijing Advanced Innovation Centre for Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, People's Republic of China.
Jianwen HuangZhuhai Interventional Medical Centre, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Zhuhai, People's Republic of China.
Di DongCAS Key Laboratory of Molecular Imaging, Beijing Key Laboratory of Molecular Imaging, The State Key Laboratory of Management and Control for Complex Systems, Institute of Automation, Chinese Academy of Sciences, Beijing, People's Republic of China.
Chongyang DuanDepartment of Biostatistics, School of Public Health, Southern Medical University, Guangzhou, People's Republic of China.ORCID 0000-0001-7973-0353
Xiaoqun LiDepartment of Interventional Treatment, Zhongshan City People's Hospital, Zhongshan, People's Republic of China.
Shuo WangBeijing Advanced Innovation Centre for Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, People's Republic of China.
Xudong ChenDepartment of Radiology, Shenzhen People's Hospital, Shenzhen, People's Republic of China.
Xiaofeng HeInterventional Diagnosis and Treatment Department, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Jianfeng YanDepartment of Radiology, Yangjiang People's Hospital, Yangjiang, People's Republic of China.
Ligong LuZhuhai Interventional Medical Centre, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Zhuhai, People's Republic of China.
Jie TianBeijing Advanced Innovation Centre for Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University, Beijing, People's Republic of China.ORCID 0000-0003-0498-0432
Chinese Academy of Sciences · CNJinan University · CNNanfang Hospital · CNQujiang People's Hospital · CNShenZhen People’s Hospital · CNSouthern Medical University · CNZhongshan People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFor timely treatment of extrahepatic metastasis and macrovascular invasion (aggressive progressive disease [PD]) in hepatocellular carcinoma, models aimed at stratifying the risks of subsequent aggressive PD should be constructed. PATIENTS AND

methodsAfter dividing 332 patients from five hospitals into training (n = 236) and validation (n = 96) datasets, non-invasive models, including clinical/semantic factors (Model

resultsAmong the constructed models, Model

conclusionOur deep learning-based model successfully stratified the risks of aggressive PD. In the high-risk population, current guideline indicates that first-line treatments are insufficient to prevent extrahepatic metastasis and macrovascular invasion and ensure survival benefits, so more therapies may be explored for these patients.

Indexed as

aggressive disease progressionclinical factorsdeep learning radiomicshigh-riskrisk prediction

Identifiers

PMID34513748
PMCPMC8427842
OpenAlexW3197675242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.