Evidence map›Paper›PMID 34513675›Full record

ArticleFrontiers in oncology2021

Imaging Hallmarks of the Tumor Microenvironment in Glioblastoma Progression.

John J Walsh, Maxime Parent, Adil Akif, Lucas C Adam, Samuel Maritim, Sandeep K Mishra, Muhammad H Khan, Daniel Coman, Fahmeed Hyder

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

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  13. Ion Channels in Gliomas-From Molecular Basis to Treatment.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

John J WalshDepartment of Biomedical Engineering, Yale University, New Haven, CT, United States.
Maxime ParentDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States.
Adil AkifDepartment of Biomedical Engineering, Yale University, New Haven, CT, United States.
Lucas C AdamDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States.
Samuel MaritimDepartment of Biomedical Engineering, Yale University, New Haven, CT, United States.
Sandeep K MishraDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States.
Muhammad H KhanDepartment of Biomedical Engineering, Yale University, New Haven, CT, United States.
Daniel ComanDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States.
Fahmeed HyderDepartment of Biomedical Engineering, Yale University, New Haven, CT, United States.
Yale University · USResonance Research (United States) · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Glioblastoma progression involves multifaceted changes in vascularity, cellularity, and metabolism. Capturing such complexities of the tumor niche, from the tumor core to the periphery, by magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI) methods has translational impact. In human-derived glioblastoma models (U87, U251) we made simultaneous and longitudinal measurements of tumor perfusion (F

Indexed as

cellularitychemical shift imagingdynamic contrast enhanced imagingextracellular pHglioblastomaMRItumor microenvironmentvascularity

Identifiers

PMID34513675
PMCPMC8426346
OpenAlexW3197298915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.