ReviewRestorative dentistry & endodontics2021
Silver nanoparticles in endodontics: recent developments and applications.
Review in Restorative dentistry & endodontics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of silver and vanadium-based antibiofilm agents: mechanisms and efficacy in oral biofilms.Future microbiology · 2025Pooled it
- Comparative in vitro evaluation of sonic, passive ultrasonic, and Er: YAG laser-activated irrigation on Enterococcus faecalis reduction and smear layer/debris removal in root canals.BMC oral health · 2026Article
- Green-SynthesizedJournal of functional biomaterials · 2026Article
- Nanoparticle-Assisted Endodontic Irrigation: A Systematic Review of Preclinical Studies.Clinical, cosmetic and investigational dentistry · 2026Review
- Scoping review on the genotoxicity of silver nanoparticles in endodontics: therapeutic saviors or genetic saboteurs?Odontology · 2025Article
- Bioceramics in Endodontics: Limitations and Future Innovations-A Review.Dentistry journal · 2025Review
- Antibacterial activity of novel nanoparticles against persistent endodontic pathogens.Bioinformation · 2025Article
- The Push-Out Bond Strength, Surface Roughness, and Antimicrobial Properties of Endodontic Bioceramic Sealers Supplemented with Silver Nanoparticles.Molecules (Basel, Switzerland) · 2024Article
- Review
- A narrative review on application of metal and metal oxide nanoparticles in endodontics.Heliyon · 2024Review
- Improving the Antimicrobial Potency of Berberine for Endodontic Canal Irrigation Using Polymeric Nanoparticles.Pharmaceutics · 2024Article
- The Effectiveness of Silver Nanoparticles Mixed with Calcium Hydroxide againstMicroorganisms · 2024Article
- Silver Nanoparticles and Their Therapeutic Applications in Endodontics: A Narrative Review.Pharmaceutics · 2023Review
- Review
- Evaluation of the efficacy of a novel disinfecting material on the surface topography of gutta-percha: AnJournal of conservative dentistry : JCDArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The elimination of endodontic biofilms and the maintenance of a leak-proof canal filling are key aspects of successful root canal treatment. Several materials have been introduced to treat endodontic disease, although treatment success is limited by the features of the biomaterials used. Silver nanoparticles (AgNPs) have been increasingly considered in dental applications, especially endodontics, due to their high antimicrobial activity. For the present study, an electronic search was conducted using MEDLINE (PubMed), the Cochrane Central Register of Controlled Trials (CENTRAL), Google Scholar, and EMBASE. This review provides insights into the unique characteristics of AgNPs, including their chemical, physical, and antimicrobial properties; limitations; and potential uses. Various studies involving different application methods of AgNPs were carefully examined. Based on previous clinical studies, the synthesis, means of obtaining, usage conditions, and potential cytotoxicity of AgNPs were evaluated. The findings indicate that AgNPs are effective antimicrobial agents for the elimination of endodontic biofilms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.