Evidence map›Paper›PMID 34513619›Full record

ReviewAdvanced pharmaceutical bulletin2021

Importance of Nano Medicine and New Drug Therapies for Cancer.

Arash Abdolmaleki, Asadollah Asadi, Krishnamoorthy Gurushankar, Tahereh Karimi Shayan, Fatemeh Abedi Sarvestani

Abstract readReview
In one paragraph

Review in Advanced pharmaceutical bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Arash AbdolmalekiDepartment of Engineering Sciences, Faculty of Advanced Technologies, University of Mohaghegh Ardabili, Namin, Iran.ORCID https://orcid.org/0000-0002-7454-8728
Asadollah AsadiDepartment of Biology, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran.ORCID https://orcid.org/0000-0003-3314-2948
Krishnamoorthy GurushankarLaboratory of Computational Modeling of Drugs, Higher Medical and Biological School, South Ural State University, Chelyabinsk-454 080, Russia.
Tahereh Karimi ShayanDepartment of Biology, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran.
Fatemeh Abedi SarvestaniDepartment of Biology, Faculty of Science, University of Mohaghegh Ardabili, Ardabil, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the deadly diseases leading to approximately 7.6 million deaths worldwide, with the mortality rate of 13%, and the number of deaths is expected to increase to 13.1 million within the next 10 years. In controlled drug delivery systems (DDS), the drug is transported to the desired location. Thus, the influence of drugs on vital tissues and undesirable side effects can be minimised. Additionally, DDS protects the drug from rapid degradation or clearance and enhances drug concentration in target tissues, and therefore, minimise the required dose of drug. This modern form of therapy is particularly important when there is a discrepancy between the dose and concentration of a drug. Cell-specific targeting can be achieved by attaching drugs to individually designed carriers. Recent developments in nanotechnology have shown that nanoparticles (particles with diameter < 100 nm in at least one dimension) have great potential as drug carriers. Because of their small size, these nanostructures exhibit unique physicochemical and biological properties that make them a favourable material for biomedical applications. Therefore, in this review, we aimed to describe the importance and types of nanomedicines and efficient ways in which new drug delivery systems for the treatment of cancer can be developed.

Indexed as

CancerDrugDrug delivery systemNanomedicine

Identifiers

PMID34513619
PMCPMC8421622

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.