ArticlePlastic and reconstructive surgery. Global open2021
Outcomes of Implant Removal and Capsulectomy for Breast Implant Illness in 248 Patients.
Article in Plastic and reconstructive surgery. Global open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Breast Implant Illness: Symptoms, Outcomes with Explantation and Potential Etiologies-A Systematic Review and Meta-analysis.Aesthetic plastic surgery · 2025Pooled it
- Comprehensive Systematic Review of Breast Implant Illness: Symptoms, Management, and Long-Term Outcomes.Aesthetic plastic surgery · 2025Pooled it
- Comprehensive Systematic Review of Breast Implant Illness: Symptoms, Management, and Long-Term Outcomes.Aesthetic plastic surgery · 2025Pooled it
- Breast implant explantation and capsulectomy in symptomatic patients. Is there any improvement with the procedure? Systematic review and meta-analysis.JPRAS open · 2026Review
- Comments on "Immediate Autologous Fat Transfer into the Breast for Volume Restoration After Implant Removal".Aesthetic plastic surgery · 2026Article
- Breast implant illness and the power of national mandatory reporting.Journal of the National Cancer Institute · 2025Article
- The Problem of Diagnostic Criteria of Breast Implant Illness in Women After Breast Reconstruction: Review and Discussion of a Case.Aesthetic plastic surgery · 2024Review
- Complications of Aesthetic and Reconstructive Breast Implant Capsulectomy: An Analysis of 7486 Patients Using Nationwide Outcomes Data.Aesthetic surgery journal · 2024Article
- Article
- Is capsulectomy necessary for symptom improvement in patients undergoing implant removal for systemic symptoms?Case reports in plastic surgery & hand surgery · 2024Article
- Biofilm-derived oxylipin 10-HOME-mediated immune response in women with breast implants.The Journal of clinical investigation · 2023Article
- Longevity of Post-Explantation Systemic Symptom Improvement and Potential Etiologies: Findings From the ASERF Systemic Symptoms in Women-Biospecimen Analysis Study: Part 4.Aesthetic surgery journal · 2023Article
- Exploring Factors Associated with Implant Removal Satisfaction in Breast Implant Illness Patients: A PRO BREAST-Q Study.Plastic and reconstructive surgery. Global open · 2023Article
- One-step Glandular Reconstruction after Breast Implant Removal: Technical Refinements and Grafting of the Inferior Dermoglandular Flap.Plastic and reconstructive surgery. Global open · 2023Article
- Breast Lift Algorithm for the Treatment of Breast Implant Illness Requiring Implant Removal.Aesthetic plastic surgery · 2023Article
- Invited Discussion on: Aesthetic Plastic Surgery Breast Lift Algorithm for the Treatment of Breast Implant Illness Requiring Implant Removal.Aesthetic plastic surgery · 2023Article
- Article
- 2022 Practice Recommendation Updates From the World Consensus Conference on BIA-ALCL.Aesthetic surgery journal · 2022Review
- Impact of Capsulectomy Type on Post-Explantation Systemic Symptom Improvement: Findings From the ASERF Systemic Symptoms in Women-Biospecimen Analysis Study: Part 1.Aesthetic surgery journal · 2022Article
- Regional Pain Blocks and Perioperative Pain Control in Patients Undergoing Breast Implant Removal With Capsulectomy.Aesthetic surgery journal. Open forum · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBreast implant illness (BII) is a term popularized by social media to describe systemic symptoms that patients ascribe to their breast implants. Though the concept of implants as an underlying cause for a systemic illness remains controversial, few studies have delineated the implant characteristics, capsular histology, and outcomes of patients who undergo explantation for BII.
methodsWe retrospectively reviewed the demographics, presenting symptoms, outcomes, capsular histology, and culture results of all women who presented to the senior author with symptoms attributed to BII and underwent breast implant removal with capsulectomy from August 2016 to February 2020. Chi-square and logistic regression analyses were performed to evaluate association between implant type, composition, and findings of inflammation on capsule pathology.
resultsAmong 248 patients, 111 (23%) capsules demonstrated inflammatory changes on permanent pathology. Capsular inflammation was independently associated with silicone versus saline (right odds ratio [OR] = 2.18 [1.16-4.11],
conclusionsIn a large cohort of BII patients, we found that capsular inflammation is significantly associated with silicone and textured implants. Implant removal with capsulectomy can be safely performed in patients with BII with a low complication rate and high patient satisfaction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.