Evidence map›Paper›PMID 34513501›Full record

ArticleCureus2021

Successful Treatment of Respiratory Syncytial Virus Infection in an Immunocompromised Patient With Ribavirin.

Wasey Ali Yadullahi Mir, Dhan B Shrestha, Wajahath Rana, Shravani Reddy Yelma Reddy, Ayusha Paudel, Larissa Verda

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

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  8. Multiplex Quantitative Analysis of 9 Compounds ofMolecules (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Wasey Ali Yadullahi MirDepartment of Internal Medicine, Mount Sinai Hospital, Chicago, USA.
Dhan B ShresthaDepartment of Internal Medicine, Mount Sinai Hospital, Chicago, USA.
Wajahath RanaDepartment of Infectious Diseases, Mount Sinai Hospital, Chicago, USA.
Shravani Reddy Yelma ReddyDepartment of Internal Medicine, SRM Medical College Hospital and Research Centre, Chennai, IND.
Ayusha PaudelDepartment of Emergency Medicine, Alka Hospital Pvt Ltd, Kathmandu, NPL.
Larissa VerdaDepartment of Internal Medicine, Mount Sinai Hospital, Chicago, USA.
ACS Medical College and Hospital · INCivil Service Hospital · NPMount Sinai Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) is a frequent cause of respiratory tract infections in children. Still, it can also cause seasonal outbreaks affecting persons of all ages, especially those with comorbidities or immunocompromised states. Ribavirin is one of the two approved therapies for the treatment of RSV respiratory tract infections. Unfortunately, its aerosolized formulation has been approved only in children, and the oral formulation is not frequently used to treat the infection. However, ribavirin has demonstrated morbidity and mortality benefit in immunocompromised patients. A 70-year-old female had started chemotherapy for a diagnosis of B-cell acute lymphoblastic leukemia (B-ALL). She developed an upper respiratory tract infection (URTI) along with positive RSV status. We started her on oral ribavirin therapy, which had to be stopped after five days of treatment due to an acute hemolytic reaction. She was re-initiated on oral ribavirin after cessation of medication for seven days and showed improvement. Therefore, ribavirin can be used in immunocompromised patients with RSV infection under proper supervision.

Indexed as

elderlyleukemiarespiratory syncytial virusrespiratory tract infectionribavirin

Identifiers

PMID34513501
PMCPMC8418695
OpenAlexW3189716790

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.