Evidence map›Paper›PMID 34513392›Full record

ArticleCureus2021

Comparative Evaluation of Nasopharyngeal and Oropharyngeal Swab Based Rapid SARS-CoV-2 Antigen Detection and Real-Time RT-PCR for Diagnosis of COVID-19 in Tertiary Care Hospital.

Arpana Singh, Pratima Gupta, Yogendra P Mathuria, Deepjyoti Kalita, Amber Prasad, Prasan K Panda, Yogesh Bahurupi, Biswajeet Sahoo, Balram Ji Omar

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Arpana SinghMicrobiology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Pratima GuptaMicrobiology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Yogendra P MathuriaMicrobiology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Deepjyoti KalitaMicrobiology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Amber PrasadMicrobiology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Prasan K PandaGeneral Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Yogesh BahurupiCommunity and Family Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Biswajeet SahooMicrobiology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Balram Ji OmarMicrobiology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Seema Dental College and Hospital · INAll India Institute of Medical Sciences Rishikesh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess and compare the diagnostic accuracy of the GenBody COVID-19 Antigen kit (GenBody Inc., Cheonan, South Korea) available in the market with the gold standard reverse transcription-polymerase chain reaction (RT-PCR) assay to detect severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

methodsNasopharyngeal and oropharyngeal swabs were collected from suspected coronavirus disease 2019 (COVID-19) patients and tested by RT-PCR and GenBody Rapid antigen kit. Performance characteristic of the antigen kit was calculated.

resultsWe tested nasopharyngeal swabs and oropharyngeal swabs (n=240). Amongst the 102 positive RT-PCR samples, the rapid antigen test detected 36 as positive, showing an overall sensitivity of 35.3%. All the samples detected positive with the antigen rapid test were also detected positive by RT-PCR.

conclusionThe performance of the rapid antigen kit was good with respect to high viral load samples, whereas those with lower levels were missed. Unfortunately, the overall low sensitivity of the antigen kit does not allow using it alone as the frontline testing kit for COVID-19 diagnosis.

Indexed as

covid 19rapid antigen testrdtrt-pcrsars cov-2

Identifiers

PMID34513392
PMCPMC8405413
OpenAlexW3188095752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.