Evidence map›Paper›PMID 34513370›Full record

ArticleCureus2021

Effectiveness of COVID-19 Convalescent Plasma Infusion Within 48 Hours of Hospitalization With SARS-CoV-2 Infection.

Natalia Lattanzio, Cristina Acosta-Diaz, Ricardo J Villasmil, Zachary Kirkland, Caitlin Bass, Sage Yenari, Jorge Conte, Kevin Dawkins, Tamela Fonseca, Cindy Grimes and 9 more

Abstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Natalia LattanzioInternal Medicine, Sarasota Memorial Hospital, Florida State University College of Medicine, Sarasota, USA.
Cristina Acosta-DiazInternal Medicine, Sarasota Memorial Hospital, Florida State University College of Medicine, Sarasota, USA.
Ricardo J VillasmilInternal Medicine, Sarasota Memorial Hospital, Florida State University College of Medicine, Sarasota, USA.
Zachary KirklandInternal Medicine, Sarasota Memorial Hospital, Florida State University College of Medicine, Sarasota, USA.
Caitlin BassInternal Medicine, Sarasota Memorial Hospital, Sarasota, USA.
Sage YenariMedicine, Sarasota Memorial Hospital, Sarasota, USA.
Jorge ConteInternal Medicine, Sarasota Memorial Hospital, Florida State University College of Medicine, Sarasota, USA.
Kevin DawkinsInternal Medicine, Sarasota Memorial Hospital, Florida State University College of Medicine, Sarasota, USA.
Tamela FonsecaClinical Research, Sarasota Memorial Hospital, Sarasota, USA.
Cindy GrimesInternal Medicine, Sarasota Memorial Hospital, Sarasota, USA.
Angie StewartClinical Database Administration, Sarasota Memorial Hospital, Sarasota, USA.
Mary E GearyQuality Improvement, Sarasota Memorial Hospital, Sarasota, USA.
Harold VorePathology, Sarasota Memorial Hospital, Sarasota, USA.
Karen HamadInternal Medicine, Sarasota Memorial Hospital, Florida State University College of Medicine, Sarasota, USA.
Wilhelmine Wiese-RometschInternal Medicine, Sarasota Memorial Hospital, Florida State University College of Medicine, Sarasota, USA.
James FioricaOncology, Sarasota Memorial Hospital, Sarasota, USA.
Manuel GordilloInfectious Disease, Sarasota Memorial Hospital, Sarasota, USA.
Roberto MercadoInfectious Disease, Sarasota Memorial Hospital, Sarasota, USA.
Kirk VoelkerPulmonology and Critical Care, Sarasota Memorial Hospital, Sarasota, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On January 30, 2020, the World Health Organization (WHO) declared the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic a worldwide emergency. Worldwide there have been 170 million cases of the resulting disease coronavirus 2019 (COVID-19), of those, 3.53 million have resulted in death. The Food and Drug Administration (FDA) with Mayo Clinic as the lead institution authorized COVID-19 convalescent plasma (CCP) for treatment of SARS-CoV-2 infection. Effective therapeutic window for CCP administration had yet to be defined. We addressed this gap by characterizing longitudinal biologic response and clinical outcomes of COVID-19 patients treated with CCP. Primary outcome was discharged to home/home health.

Indexed as

convalescent plasmacovid-19discharge to homeinfusionsars-cov-2

Identifiers

PMID34513370
PMCPMC8405359

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.