Evidence map›Paper›PMID 34513257›Full record

ArticleBiomedical optics express2021

Label-free microscopy of mitotic chromosomes using the polarization orthogonality breaking technique.

Rajesh Desapogu, Gilles Le Marchand, Rebecca Smith, Paulami Ray, Émilie Gillier, Stéphanie Dutertre, Mehdi Alouini, Marc Tramier, Sébastien Huet, Julien Fade

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Rajesh DesapoguUniv Rennes, CNRS, IGDR, UMR 6290, F-35000 Rennes, France.
Gilles Le MarchandUniv Rennes, CNRS, IGDR, UMR 6290, F-35000 Rennes, France.
Rebecca SmithUniv Rennes, CNRS, IGDR, UMR 6290, F-35000 Rennes, France.
Paulami RayUniv Rennes, CNRS, Institut FOTON-UMR 6082, F-35000 Rennes, France.
Émilie GillierUniv Rennes, CNRS, IGDR, UMR 6290, F-35000 Rennes, France.
Stéphanie DutertreUniv Rennes, BIOSIT, UMS CNRS 3480, US INSERM 018, F-35000 Rennes, France.
Mehdi AlouiniUniv Rennes, CNRS, Institut FOTON-UMR 6082, F-35000 Rennes, France.ORCID https://orcid.org/0000-0001-7943-5290
Marc TramierUniv Rennes, CNRS, IGDR, UMR 6290, F-35000 Rennes, France.
Sébastien HuetUniv Rennes, CNRS, IGDR, UMR 6290, F-35000 Rennes, France.
Julien FadeUniv Rennes, CNRS, Institut FOTON-UMR 6082, F-35000 Rennes, France.ORCID https://orcid.org/0000-0003-3371-8775
Université Rennes 2 · FRInstitut Universitaire de France · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report how a recently developed polarization imaging technique, implementing micro-wave photonics and referred to as orthogonality-breaking (OB) imaging, can be adapted on a classical confocal fluorescence microscope, and is able to provide informative polarization images from a single scan of the cell sample. For instance, the comparison of the images of various cell lines at different cell-cycle stages obtained by OB polarization microscopy and fluorescence confocal images shows that an endogenous polarimetric contrast arizes with this instrument on compacted chromosomes during cell division.

Identifiers

PMID34513257
PMCPMC8407833
OpenAlexW3171627459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.