Evidence map›Paper›PMID 34513247›Full record

ArticleBiomedical optics express2021

Rapid pseudo-H&E imaging using a fluorescence-inbuilt optical coherence microscopic imaging system.

Sey-En Lin, Dong-Yo Jheng, Kuang-Yu Hsu, Yun-Ru Liu, Wei-Hsiang Huang, Hsiang-Chieh Lee, Chien-Chung Tsai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Tissue harvest with a laser microbiopsy.Journal of biomedical optics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sey-En LinAcuSolutions Inc., 3F., No. 2, Ln. 263, Chongyang Rd., Nangang Dist., Taipei, Taiwan.ORCID https://orcid.org/0000-0002-8994-9452
Dong-Yo JhengAcuSolutions Inc., 3F., No. 2, Ln. 263, Chongyang Rd., Nangang Dist., Taipei, Taiwan.
Kuang-Yu HsuAcuSolutions Inc., 3F., No. 2, Ln. 263, Chongyang Rd., Nangang Dist., Taipei, Taiwan.
Yun-Ru LiuJoint Biobank, Office of Human Research, Taipei Medical University, Taipei, Taiwan.
Wei-Hsiang HuangGraduate Institute of Molecular and Comparative Pathobiology, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.
Hsiang-Chieh LeeGraduate Institute of Photonics and Optoelectronics, National Taiwan University, Taipei, Taiwan.ORCID https://orcid.org/0000-0002-2976-6195
Chien-Chung TsaiAcuSolutions Inc., 3F., No. 2, Ln. 263, Chongyang Rd., Nangang Dist., Taipei, Taiwan.ORCID https://orcid.org/0000-0002-6960-3753

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A technique using Linnik-based optical coherence microscopy (OCM), with built-in fluorescence microscopy (FM), is demonstrated here to describe cellular-level morphology for fresh porcine and biobank tissue specimens. The proposed method utilizes color-coding to generate digital pseudo-H&E (p-H&E) images. Using the same camera, colocalized FM images are merged with corresponding morphological OCM images using a 24-bit RGB composition process to generate position-matched p-H&E images. From receipt of dissected fresh tissue piece to generation of stitched images, the total processing time is <15 min for a 1-cm

Identifiers

PMID34513247
PMCPMC8407814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.