Evidence map›Paper›PMID 34513234›Full record

ArticleBiomedical optics express2021

Closed-loop wavefront sensing and correction in the mouse brain with computed optical coherence microscopy.

Siyang Liu, Fei Xia, Xusan Yang, Meiqi Wu, Laurie A Bizimana, Chris Xu, Steven G Adie

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Siyang LiuSchool of Electrical and Computer Engineering, Cornell University, Ithaca, NY 14853, USA.
Fei XiaMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.ORCID https://orcid.org/0000-0001-6591-8769
Xusan YangSchool of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA.ORCID https://orcid.org/0000-0001-8429-6299
Meiqi WuMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.
Laurie A BizimanaMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.
Chris XuSchool of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA.
Steven G AdieMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.
Cornell University · US

Funding

Real-time Aberration Sensor for Large-Scale Microscopy Deep in the Mouse and Adult Zebrafish BrainR01NS120819 · NINDS · CORNELL UNIVERSITY · PI ADIE, STEVEN GRAHAM · 2021 to 2021
$2.0M
Development of Hybrid Adaptive Optics for Multimodal Microscopy Deep in the Mouse BrainR21EY028389 · NEI · CORNELL UNIVERSITY · PI ADIE, STEVEN GRAHAM · 2017 to 2018
$491k
Volumetric Traction Force Tomography of Collective Cell Migration DynamicsR21EB022927 · NIBIB · CORNELL UNIVERSITY · PI ADIE, STEVEN GRAHAM · 2016 to 2017
$434k
NEI NIH HHS R21 EY028389NIBIB NIH HHS R21 EB022927NINDS NIH HHS R01 NS120819
6 · The paper itself

Abstract

Optical coherence microscopy (OCM) uses interferometric detection to capture the complex optical field with high sensitivity, which enables computational wavefront retrieval using back-scattered light from the sample. Compared to a conventional wavefront sensor, aberration sensing with OCM via computational adaptive optics (CAO) leverages coherence and confocal gating to obtain signals from the focus with less cross-talk from other depths or transverse locations within the field-of-view. Here, we present an investigation of the performance of CAO-based aberration sensing in simulation, bead phantoms, and

Identifiers

PMID34513234
PMCPMC8407825
OpenAlexW3185855971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.