Evidence map›Paper›PMID 34513115›Full record

ReviewJournal of pharmaceutical analysis2021

Drug repurposing against coronavirus disease 2019 (COVID-19): A review.

Lianxiang Luo, Qin Qiu, Fangfang Huang, Kaifeng Liu, Yongqi Lan, Xiaoling Li, Yuge Huang, Liao Cui, Hui Luo

Abstract readReview
In one paragraph

Review in Journal of pharmaceutical analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Current clinical status of new COVID-19 vaccines and immunotherapy.Environmental science and pollution research international · 2022
    Review
  4. Drug repurposing for the treatment of COVID-19.Journal of pharmacological sciences · 2022
    Review
  5. Article
  6. Potential Multifunctional Bioactive Compounds fromJournal of inflammation research · 2022
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lianxiang LuoMarine Biomedical Research Institute, Guangdong Medical University, Zhanjiang, 524023, Guangdong, China.
Qin QiuGraduate School, Guangdong Medical University, Zhanjiang, 524023, Guangdong, China.
Fangfang HuangGraduate School, Guangdong Medical University, Zhanjiang, 524023, Guangdong, China.
Kaifeng LiuThe First Clinical College, Guangdong Medical University, Zhanjiang, 524023, Guangdong, China.
Yongqi LanThe First Clinical College, Guangdong Medical University, Zhanjiang, 524023, Guangdong, China.
Xiaoling LiAnimal Experiment Center, Guangdong Medical University, Zhanjiang, 524023, Guangdong, China.
Yuge HuangDepartment of Pediatrics, the Affiliated Hospital of Guangdong Medical University, Zhanjiang, 524023, Guangdong, China.
Liao CuiGuangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical University, Zhanjiang, 524023, Guangdong, China.
Hui LuoMarine Biomedical Research Institute, Guangdong Medical University, Zhanjiang, 524023, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since December 2019, severe acute respiratory syndrome coronavirus 2 has been found to be the culprit in the coronavirus disease 2019 (COVID-19), causing a global pandemic. Despite the existence of many vaccine programs, the number of confirmed cases and fatalities due to COVID-19 is still increasing. Furthermore, a number of variants have been reported. Because of the absence of approved anti-coronavirus drugs, the treatment and management of COVID-19 has become a global challenge. Under these circumstances, drug repurposing is an effective method to identify candidate drugs with a shorter cycle of clinical trials. Here, we summarize the current status of the application of drug repurposing in COVID-19, including drug repurposing based on virtual computer screening, network pharmacology, and bioactivity, which may be a beneficial COVID-19 treatment.

Indexed as

3C-like proteaseCOVID-19Drug repurposingSARS-CoV-2Virtual screening

Identifiers

PMID34513115
PMCPMC8416689

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.