Evidence map›Paper›PMID 34513087›Full record

ArticleJournal of ophthalmology2021

The Diagnostic Capability of Swept Source OCT Angiography in Treatment-Naive Exudative Neovascular Age-Related Macular Degeneration.

Daniel Ahmed, Martin Stattin, Anna-Maria Haas, Stefan Kickinger, Maximilian Gabriel, Alexandra Graf, Katharina Krepler, Siamak Ansari-Shahrezaei

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Article in Journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel AhmedKarl Landsteiner Institute for Retinal Research and Imaging, Rudolf Foundation Hospital, Juchgasse 25, Vienna 1030, Austria.
Martin StattinKarl Landsteiner Institute for Retinal Research and Imaging, Rudolf Foundation Hospital, Juchgasse 25, Vienna 1030, Austria.
Anna-Maria HaasKarl Landsteiner Institute for Retinal Research and Imaging, Rudolf Foundation Hospital, Juchgasse 25, Vienna 1030, Austria.
Stefan KickingerKarl Landsteiner Institute for Retinal Research and Imaging, Rudolf Foundation Hospital, Juchgasse 25, Vienna 1030, Austria.
Maximilian GabrielKarl Landsteiner Institute for Retinal Research and Imaging, Rudolf Foundation Hospital, Juchgasse 25, Vienna 1030, Austria.
Alexandra GrafCenter for Medical Statistic Informatics and Intelligent Systems, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria.
Katharina KreplerKarl Landsteiner Institute for Retinal Research and Imaging, Rudolf Foundation Hospital, Juchgasse 25, Vienna 1030, Austria.
Siamak Ansari-ShahrezaeiKarl Landsteiner Institute for Retinal Research and Imaging, Rudolf Foundation Hospital, Juchgasse 25, Vienna 1030, Austria.ORCID https://orcid.org/0000-0001-8032-4686

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the capability of swept source-optical coherence tomography angiography (SS-OCTA) in the detection and localization of treatment-naive macular neovascularization (MNV) secondary to exudative neovascular age-related macular degeneration (nAMD).

methodsIn this prospective, observational case series, 158 eyes of 142 patients were diagnosed with exudative nAMD using fluorescein (FA) and indocyanine green angiography (ICGA) and evaluated by SS-OCTA in a tertiary retina center (Rudolf Foundation Hospital Vienna, Austria). The main outcome measure was the sensitivity of SS-OCTA compared to the standard multimodal imaging approach. Secondary outcome measure was the anatomic analysis of MNV in relation to the retinal pigment epithelium.

resultsEn-face SS-OCTA confirmed a MNV in 126 eyes (sensitivity: 79.8%), leaving 32 eyes (20.2%) undetected. In 23 of these 32 eyes (71.9%), abnormal flow in cross-sectional SS-OCTA B-scans was identified, giving an overall SS-OCTA sensitivity of 94.3%. Eyes with a pigment epithelium detachment (PED) ≥ 300

conclusionsSS-OCTA remains inferior to dye-based angiography in the detection rate of exudative nAMD consistent with type 1 MNV and a PED ≥300

Identifiers

PMID34513087
PMCPMC8429016

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