Evidence map›Paper›PMID 34512994›Full record

ArticleConservation physiology2021

Applied ecoimmunology: using immunological tools to improve conservation efforts in a changing world.

Michel E B Ohmer, David Costantini, Gábor Á Czirják, Cynthia J Downs, Laura V Ferguson, Andy Flies, Craig E Franklin, Ahab N Kayigwe, Sarah Knutie, Corinne L Richards-Zawacki and 1 more

Open access · goldAbstract read
In one paragraph

Article in Conservation physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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  13. Introduction to the special issue Amphibian immunity: stress, disease and ecoimmunology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 5 countries.

Michel E B OhmerLiving Earth Collaborative, Washington University in St. Louis, MO 63130, USA.
David CostantiniUnité Physiologie Moléculaire et Adaptation (PhyMA), Muséum National d'Histoire Naturelle, CNRS, 57 Rue Cuvier, CP32, 75005, Paris, France.
Gábor Á CzirjákDepartment of Wildlife Diseases, Leibniz Institute for Zoo and Wildlife Research, 10315 Berlin, Germany.
Cynthia J DownsDepartment of Environmental Biology, SUNY College of Environmental Science and Forestry, Syracuse, NY 13210, USA.
Laura V FergusonDepartment of Psychology and Neuroscience, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Andy FliesMenzies Institute for Medical Research, University of Tasmania, Tasmania 7001, Australia.
Craig E FranklinSchool of Biological Sciences, The University of Queensland, Queensland 4072, Australia.
Ahab N KayigweMenzies Institute for Medical Research, University of Tasmania, Tasmania 7001, Australia.
Sarah KnutieDepartment of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT 06268, USA.
Corinne L Richards-ZawackiDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Rebecca L CrampSchool of Biological Sciences, The University of Queensland, Queensland 4072, Australia.
University of Queensland · AUUniversity of Tasmania · AUDalhousie University · CAÉco-Anthropologie · FRLeibniz Institute for Zoo and Wildlife Research · DEPurchase College · USUniversity of Connecticut · USUniversity of Pittsburgh · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ecoimmunology is a rapidly developing field that explores how the environment shapes immune function, which in turn influences host-parasite relationships and disease outcomes. Host immune defence is a key fitness determinant because it underlies the capacity of animals to resist or tolerate potential infections. Importantly, immune function can be suppressed, depressed, reconfigured or stimulated by exposure to rapidly changing environmental drivers like temperature, pollutants and food availability. Thus, hosts may experience trade-offs resulting from altered investment in immune function under environmental stressors. As such, approaches in ecoimmunology can provide powerful tools to assist in the conservation of wildlife. Here, we provide case studies that explore the diverse ways that ecoimmunology can inform and advance conservation efforts, from understanding how Galapagos finches will fare with introduced parasites, to using methods from human oncology to design vaccines against a transmissible cancer in Tasmanian devils. In addition, we discuss the future of ecoimmunology and present 10 questions that can help guide this emerging field to better inform conservation decisions and biodiversity protection. From better linking changes in immune function to disease outcomes under different environmental conditions, to understanding how individual variation contributes to disease dynamics in wild populations, there is immense potential for ecoimmunology to inform the conservation of imperilled hosts in the face of new and re-emerging pathogens, in addition to improving the detection and management of emerging potential zoonoses.

Identifiers

PMID34512994
PMCPMC8422949
OpenAlexW3196302940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.