Evidence map›Paper›PMID 34512909›Full record

ArticleWorld journal of gastrointestinal surgery2021

Impact of COVID-19 on presentation, management, and outcomes of acute care surgery for gallbladder disease and acute appendicitis.

Orly Nadell Farber, Giselle I Gomez, Ashley L Titan, Andrea T Fisher, Christopher J Puntasecca, Veronica Toro Arana, Arielle Kempinsky, Clare E Wise, Kovi E Bessoff, Mary T Hawn and 3 more

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in World journal of gastrointestinal surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05104346 (Presentation and Outcomes of Acute Appendicitis During COVID Pandemic), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05104346 nacompletednot on this map

Presentation and Outcomes of Acute Appendicitis During COVID Pandemic: Lessons Learned From the Middle East (Multicenter Study)

TypeinterventionalSponsorMansoura UniversityRan2019 to 2021Enrolled1,945ConditionsAcute AppendicitisArmsappendectomy
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. [Impact of COVID-19 on gallbladder disease: presentation of postponed surgeries].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Important role of acute care surgery during pandemic time.World journal of gastrointestinal surgery · 2022
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Orly Nadell FarberDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Giselle I GomezDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Ashley L TitanDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Andrea T FisherDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Christopher J PuntaseccaDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Veronica Toro AranaDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Arielle KempinskyDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Clare E WiseDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Kovi E BessoffDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Mary T HawnDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
James R KorndorfferDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Joseph D ForresterDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Micaela M EsquivelDepartment of Surgery, Stanford University School of Medicine, Palo Alto, CA 94305, United States. mesquive@stanford.edu.
Palo Alto University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ongoing coronavirus disease 2019 (COVID-19) pandemic has significantly disrupted both elective and acute medical care. Data from the early months suggest that acute care patient populations deferred presenting to the emergency department (ED), portending more severe disease at the time of presentation. Additionally, care for this patient population trended towards initial non-operative management.

aimTo examine the presentation, management, and outcomes of patients who developed gallbladder disease or appendicitis during the pandemic.

methodsA retrospective chart review of patients diagnosed with acute cholecystitis, symptomatic cholelithiasis, or appendicitis in two EDs affiliated with a single tertiary academic medical center in Northern California between March and June, 2020 and in the same months of 2019. Patients were selected through a research repository using international classification of diseases (ICD)-9 and ICD-10 codes. Across both years, 313 patients were identified with either type of gallbladder disease, while 361 patients were identified with acute appendicitis. The primary outcome was overall incidence of disease. Secondary outcomes included presentation, management, complications, and 30-d re-presentation rates. Relationships between different variables were explored using Pearson's r correlation coefficient. Variables were compared using the Welch's t-Test, Chi-squared tests, and Fisher's exact test as appropriate.

resultsPatients with gallbladder disease and appendicitis both had more severe presentations in 2020. With respect to gallbladder disease, more patients in the COVID-19 cohort presented with acute cholecystitis compared to the control cohort [50% (80)

conclusionDuring the COVID-19 pandemic, patients presented with more severe gallbladder disease and appendicitis. These findings suggest that the pandemic has affected patients with acute surgical conditions.

Indexed as

Acute care surgeryAppendicitisBiliary colicCholecystitisCOVID-19

Identifiers

PMID34512909
PMCPMC8394376
OpenAlexW3193446907

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.