Evidence map›Paper›PMID 34512871›Full record

ArticleOxidative medicine and cellular longevity2021

Cardiovascular Properties of the Androgen-Induced PCOS Model in Rats: The Role of Oxidative Stress.

Jovana Joksimovic Jovic, Jasmina Sretenovic, Nikola Jovic, Jovan Rudic, Vladimir Zivkovic, Ivan Srejovic, Katarina Mihajlovic, Nevena Draginic, Marijana Andjic, Milica Milinkovic and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Reproductive and Cardiometabolic Characterization of a Letrozole- and High-Fat Diet-Induced PMOS-like Rat Model: An Experimental Study.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Article
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  16. Antioxidative Effects of StandardizedAntioxidants (Basel, Switzerland) · 2022
    Article
  17. Article
  18. Fertility-enhancing effects ofAvicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 2 countries.

Jovana Joksimovic JovicDepartment of Physiology, University of Kragujevac, Faculty of Medical Sciences, Svetozara Markovica 69, 34000 Kragujevac, Serbia.ORCID https://orcid.org/0000-0001-9625-0626
Jasmina SretenovicDepartment of Physiology, University of Kragujevac, Faculty of Medical Sciences, Svetozara Markovica 69, 34000 Kragujevac, Serbia.ORCID https://orcid.org/0000-0001-5849-1998
Nikola JovicDepartment of Gynecology and Obstetrics, University of Kragujevac, Faculty of Medical Sciences, Svetozara Markovica 69, 34000 Kragujevac, Serbia.ORCID https://orcid.org/0000-0002-3269-1577
Jovan RudicUniversity Clinic for Gynecology and Obstetrics "Narodni Front", Belgrade, Serbia.ORCID https://orcid.org/0000-0002-5294-7488
Vladimir ZivkovicDepartment of Physiology, University of Kragujevac, Faculty of Medical Sciences, Svetozara Markovica 69, 34000 Kragujevac, Serbia.ORCID https://orcid.org/0000-0001-9354-9876
Ivan SrejovicDepartment of Physiology, University of Kragujevac, Faculty of Medical Sciences, Svetozara Markovica 69, 34000 Kragujevac, Serbia.ORCID https://orcid.org/0000-0002-3835-1856
Katarina MihajlovicDepartment of Pharmacy, University of Kragujevac, Faculty of Medical Sciences, Svetozara Markovica 69, 34000 Kragujevac, Serbia.ORCID https://orcid.org/0000-0003-1975-1990
Nevena DraginicDepartment of Pharmacy, University of Kragujevac, Faculty of Medical Sciences, Svetozara Markovica 69, 34000 Kragujevac, Serbia.ORCID https://orcid.org/0000-0001-9684-0925
Marijana AndjicDepartment of Pharmacy, University of Kragujevac, Faculty of Medical Sciences, Svetozara Markovica 69, 34000 Kragujevac, Serbia.ORCID https://orcid.org/0000-0002-7785-8203
Milica MilinkovicDepartment of Physiology, University of Kragujevac, Faculty of Medical Sciences, Svetozara Markovica 69, 34000 Kragujevac, Serbia.ORCID https://orcid.org/0000-0002-3912-5404
Zoran MilosavljevicDepartment of Histology and Embryology, University of Kragujevac, Faculty of Medical Sciences, Svetozara Markovica 69, 34000 Kragujevac, Serbia.ORCID https://orcid.org/0000-0002-6078-0665
Vladimir JakovljevicDepartment of Physiology, University of Kragujevac, Faculty of Medical Sciences, Svetozara Markovica 69, 34000 Kragujevac, Serbia.ORCID https://orcid.org/0000-0002-0071-8376
University of Kragujevac · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is a multifaced reproductive endocrinopathy affecting 6-20% of women of childbearing age. It was previously shown that women with PCOS have an increased risk of cardiovascular (CV) diseases. The aim of this study was to evaluate the cardiodynamic parameters of isolated rats' hearts, blood pressure levels, and histomorphological changes in the heart tissue following the androgen-induced PCOS model in rats and the role of oxidative stress in the development of these CV properties of PCOS. 21-day-old female rats (

Indexed as

AnimalsCardiovascular DiseasesDisease Models, AnimalFemaleHumansOxidative StressPolycystic Ovary SyndromeRatsRats, WistarTestosteroneTestosteronetestosterone enanthate

Identifiers

PMID34512871
PMCPMC8426083
OpenAlexW3196680243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.