Evidence map›Paper›PMID 34512782›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Paeoniflorin Protects against ANIT-Induced Cholestatic Liver Injury in Rats via the Activation of SIRT1-FXR Signaling Pathway.

Lisheng Chen, Shizhang Wei, Honghong Liu, Jianyu Li, Manyi Jing, Yuling Tong, Ruisheng Li, Jianxia Wen, Hanqiu Zhan, Yanling Zhao

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Involvement of SIRT1-mediated aging in liver diseases.Frontiers in cell and developmental biology · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Lisheng ChenDepartment of Pharmacy, Hebei North University, Zhangjiakou 075000, China.ORCID https://orcid.org/0000-0003-3308-0898
Shizhang WeiDepartment of Pharmacy, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Honghong LiuIntegrated TCM & Western Medicine Department, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Jianyu LiIntegrated TCM & Western Medicine Department, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Manyi JingDepartment of Pharmacy, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.ORCID https://orcid.org/0000-0002-2178-7805
Yuling TongDepartment of Pharmacy, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Ruisheng LiResearch Center for Clinical and Translational Medicine, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
Jianxia WenDepartment of Pharmacy, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.ORCID https://orcid.org/0000-0002-1184-8758
Hanqiu ZhanDepartment of Pharmacy, Beijing Ditanhospital, Capital Medical University, Beijing 100039, China.ORCID https://orcid.org/0000-0001-5946-211X
Yanling ZhaoDepartment of Pharmacy, Hebei North University, Zhangjiakou 075000, China.ORCID https://orcid.org/0000-0003-1079-7896
Chinese PLA General Hospital · CNHebei North University · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paeoniflorin (PF), a water-soluble monoterpene glycoside, is initially isolated from the dried roots of

Identifiers

PMID34512782
PMCPMC8429014
OpenAlexW3196829607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.