Evidence map›Paper›PMID 34512633›Full record

ReviewFrontiers in immunology2021

The Role of the Adhesion Receptor CD146 and Its Soluble Form in Human Embryo Implantation and Pregnancy.

Sylvie Bouvier, Elise Kaspi, Ahmad Joshkon, Odile Paulmyer-Lacroix, Marie-Dominique Piercecchi-Marti, Akshita Sharma, Aurélie S Leroyer, Alexandrine Bertaud, Jean-Christophe Gris, Françoise Dignat-George and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 3 countries.

Sylvie BouvierDepartment of Hematology, Nîmes University Hospital, Nîmes, France.
Elise KaspiAix Marseille Univ, APHM, INSERM, MMG, Hôpital la Timone, Service de Biologie Cellulaire, Marseille, France.
Ahmad JoshkonAix-Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Odile Paulmyer-LacroixAix Marseille Univ, APHM, Hôpital la Conception, Laboratory of Histology-Embryology/Biology of Reproduction, Marseille, France.
Marie-Dominique Piercecchi-MartiAix Marseille Univ, APHM, CNRS, EFS, ADES, Hôpital La Timone, Forensic Department, Marseille, France.
Akshita SharmaDepartment of Stem Cell and Regenerative Medicine, Centre for Interdisciplinary Research, DY Patil University, Kolhapur, India.
Aurélie S LeroyerAix-Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Alexandrine BertaudAix-Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Jean-Christophe GrisDepartment of Hematology, Nîmes University Hospital, Nîmes, France.
Françoise Dignat-GeorgeAix Marseille Univ, APHM, INSERM, INRAE, C2VN, Hôpital la Conception, Laboratoire d'Hématologie, Marseille, France.
Marcel Blot-ChabaudAix-Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Nathalie BardinAix Marseille Univ, APHM, INSERM, INRAE, C2VN, Hôpital la Conception, Laboratoire d'Immunologie, Marseille, France.
Aix-Marseille Université · FRHôpital de la Conception · FRUnité de recherche sur les maladies cardiovasculaires et métaboliques · FRCentre de Génétique Médicale de MarseilleCentre Hospitalier Universitaire de Nîmes · FRCentre National de la Recherche Scientifique · FRD.Y. Patil University · INSechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD146 is an adhesion molecule essentially located in the vascular system, which has been described to play an important role in angiogenesis. A soluble form of CD146, called sCD146, is detected in the bloodstream and is known as an angiogenic factor. During placental development, CD146 is selectively expressed in extravillous trophoblasts. A growing body of evidence shows that CD146 and, in particular, sCD146, regulate extravillous trophoblasts migration and invasion both

Indexed as

Embryo ImplantationBiomarkersCD146 AntigenFemaleHumansPregnancyBiomarkersCD146 AntigenbiomarkerCD146/sCD146fertilityimplantationpreeclampsiapregnancy

Identifiers

PMID34512633
PMCPMC8427600
OpenAlexW3197419905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.