Evidence map›Paper›PMID 34512507›Full record

ArticleFrontiers in neurology2021

Intestinal Permeability and Circulating CD161+CCR6+CD8+T Cells in Patients With Relapsing-Remitting Multiple Sclerosis Treated With Dimethylfumarate.

Maria C Buscarinu, Francesca Gargano, Luana Lionetto, Matilde Capi, Emanuele Morena, Arianna Fornasiero, Roberta Reniè, Anna C Landi, Giulia Pellicciari, Carmela Romano and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Impaired intestinal permeability in patients with multiple sclerosis.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2025
    Article
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Maria C BuscarinuDepartment of Neuroscience, Mental Health and Sensory Organs, Sapienza University, Rome, Italy.
Francesca GarganoNeuroimmunology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy.
Luana LionettoMass Spectrometry Section, Laboratory of Clinical Biochemistry Sant'Andrea University Hospital, Rome, Italy.
Matilde CapiMass Spectrometry Section, Laboratory of Clinical Biochemistry Sant'Andrea University Hospital, Rome, Italy.
Emanuele MorenaDepartment of Neuroscience, Mental Health and Sensory Organs, Sapienza University, Rome, Italy.
Arianna FornasieroDepartment of Neuroscience, Mental Health and Sensory Organs, Sapienza University, Rome, Italy.
Roberta RenièDepartment of Clinical-Experimental Neuroscience and Psychiatry, Sapienza University, Rome, Italy.
Anna C LandiDepartment of Neuroscience, Mental Health and Sensory Organs, Sapienza University, Rome, Italy.
Giulia PellicciariDepartment of Neuroscience, Mental Health and Sensory Organs, Sapienza University, Rome, Italy.
Carmela RomanoDepartment of Clinical-Experimental Neuroscience and Psychiatry, Sapienza University, Rome, Italy.
Rosella MechelliDepartment of Human Science and Promotion of Quality of Life, San Raffaele Roma Open University, Rome, Italy.
Silvia RomanoDepartment of Neuroscience, Mental Health and Sensory Organs, Sapienza University, Rome, Italy.
Giovanna BorsellinoNeuroimmunology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy.
Luca BattistiniNeuroimmunology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Fondazione Santa Lucia, Rome, Italy.
Maurizio SimmacoDepartment of Neuroscience, Mental Health and Sensory Organs, Sapienza University, Rome, Italy.
Corrado FagnaniCenter for Behavioral Sciences and Mental Health, Higher Institute of Health (ISS), Rome, Italy.
Marco SalvettiDepartment of Neuroscience, Mental Health and Sensory Organs, Sapienza University, Rome, Italy.
Giovanni RistoriDepartment of Neuroscience, Mental Health and Sensory Organs, Sapienza University, Rome, Italy.
Sapienza University of Rome · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITCTO Andrea Alesini · ITFondazione Santa Lucia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CD161+CCR6+CD8+T cellsdimethyl-fumarateintestinal permeabilitymucosal immunitymultiple sclerosis

Identifiers

PMID34512507
PMCPMC8426620
OpenAlexW3198800360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.