Evidence map›Paper›PMID 34512388›Full record

ArticleFrontiers in physiology2021

Autophagy Induces Expression of IL-6 in Human Periodontal Ligament Fibroblasts Under Mechanical Load and Overload and Effects Osteoclastogenesis

Alexandra Mayr, Jana Marciniak, Benedikt Eggers, Kim Blawat, Jan Wildenhof, Rogerio Bastos Craveiro, Michael Wolf, James Deschner, Andreas Jäger, Svenja Beisel-Memmert

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Alexandra MayrDepartment of Orthodontics, Center of Dento-Maxillo-Facial Medicine, University of Bonn Medical Center, Bonn, Germany.
Jana MarciniakDepartment of Orthodontics, Center of Dento-Maxillo-Facial Medicine, University of Bonn Medical Center, Bonn, Germany.
Benedikt EggersDepartment of Oral, Maxillofacial and Plastic Surgery, Center of Dento-Maxillo-Facial Medicine, University of Bonn Medical Center, Bonn, Germany.
Kim BlawatDepartment of Orthodontics, Center of Dento-Maxillo-Facial Medicine, University of Bonn Medical Center, Bonn, Germany.
Jan WildenhofPrivate Clinic Schloss Schellenstein, Olsberg, Germany.
Rogerio Bastos CraveiroDepartment of Orthodontics, Faculty of Medicine, University Hospital Aachen, Aachen, Germany.
Michael WolfDepartment of Orthodontics, Faculty of Medicine, University Hospital Aachen, Aachen, Germany.
James DeschnerDepartment of Periodontology and Operative Dentistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Andreas JägerDepartment of Orthodontics, Center of Dento-Maxillo-Facial Medicine, University of Bonn Medical Center, Bonn, Germany.
Svenja Beisel-MemmertDepartment of Orthodontics, Center of Dento-Maxillo-Facial Medicine, University of Bonn Medical Center, Bonn, Germany.
University of Bonn · DEUniversitätsklinikum Aachen · DEUniversity Medical Center of the Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ADAM10ADAM17autophagycell-cell communicationhuman periodontal ligament fibroblastsIL-6mechanical loadmechanical overload

Identifiers

PMID34512388
PMCPMC8430222
OpenAlexW3196363843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.