Evidence map›Paper›PMID 34512305›Full record

ArticleFrontiers in aging neuroscience2021

Mindfulness Training Improves Cognition and Strengthens Intrinsic Connectivity Between the Hippocampus and Posteromedial Cortex in Healthy Older Adults.

Gunes Sevinc, Johann Rusche, Bonnie Wong, Tanya Datta, Robert Kaufman, Sarah E Gutz, Marissa Schneider, Nevyana Todorova, Christian Gaser, Götz Thomalla and 3 more

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Neuromodulation and cognition in late-life depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  5. Article
  6. Article
  7. ENIGMA-Meditation: Worldwide Consortium for Neuroscientific Investigations of Meditation Practices.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gunes SevincDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Johann RuscheDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Bonnie WongDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Tanya DattaDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Robert KaufmanDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Sarah E GutzDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Marissa SchneiderDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Nevyana TodorovaDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Christian GaserDepartment of Psychiatry and Neurology, Jena University Hospital, Jena, Germany.
Götz ThomallaKopf- und Neurozentrum, Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Dorene RentzDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Bradford D DickersonDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.
Sara W LazarDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

Funding

Research Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI STEVEN E ARNOLD · 2019 to 2026
$36.5M
Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI PUJOL, SONIA · 2012 to 2022
$20.9M
Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
Neural and cognitive changes associated with mindfulness training in older adultsR01AG048351 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI DICKERSON, BRADFORD C, LAZAR, SARA W · 2015 to 2019
$4.0M
Combined MRI/PET Imager for Simultaneous Acquisition of PET/MRI DataS10RR022976 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI JENKINS, BRUCE · 2007 to 2007
$2.0M
A Storage Area Network for Structural and Functional Image AnalysisS10RR023401 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2009 to 2009
$2.0M
SILICON GRAPHICS PRISM EXTREME 128P/1TBS10RR023043 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, ALMA GREGORY · 2006 to 2006
$1.5M
PET CAMERA FOR BRAIN IMAGING: SCHIZOPHRENIA, BIPOLAR DISORDERS10RR019933 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, ALMA GREGORY · 2006 to 2006
$500k
CYCLOTRON &RADIOCHEMISTRY: SUBSTANCE ABUSE, COCAINE, OPIOIDS10RR017208 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2004 to 2004
$500k
Carbon-11 Radiopharmaceutical Production SystemS10RR026666 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI BROWNELL, ANNA-LIISA · 2010 to 2010
$462k
NCRR NIH HHS S10 RR017208NCRR NIH HHS S10 RR019933NCRR NIH HHS S10 RR022976NCRR NIH HHS S10 RR023043NCRR NIH HHS S10 RR023401NCRR NIH HHS S10 RR026666NIA NIH HHS P30 AG062421NIA NIH HHS R01 AG048351NIBIB NIH HHS P41 EB015896NIBIB NIH HHS P41 EB015902
6 · The paper itself

Abstract

Maintaining optimal cognitive functioning throughout the lifespan is a public health priority. Evaluation of cognitive outcomes following interventions to promote and preserve brain structure and function in older adults, and associated neural mechanisms, are therefore of critical importance. In this randomized controlled trial, we examined the behavioral and neural outcomes following mindfulness training (

Indexed as

agingcognitive compositeinterventionmindfulnessresting state – fMRI

Identifiers

PMID34512305
PMCPMC8430251

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.