Evidence map›Paper›PMID 34512241›Full record

ReviewFrontiers in neuroscience2021

Pre-clinical Investigation of Rett Syndrome Using Human Stem Cell-Based Disease Models.

Florencia D Haase, Bronte Coorey, Lisa Riley, Laurence C Cantrill, Patrick P L Tam, Wendy A Gold

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Rett syndrome.Nature reviews. Disease primers · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Advances in the pathogenesis of Rett syndrome using cell models.Animal models and experimental medicine · 2022
    Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Florencia D HaaseFaculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Bronte CooreyFaculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Lisa RileyRare Diseases Functional Genomics Laboratory, Kids Research, Children's Hospital at Westmead, and Children's Medical Research Institute, Westmead, NSW, Australia.
Laurence C CantrillFaculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Patrick P L TamEmbryology Research Unit, Children's Medical Research Institute, The University of Sydney, Sydney, NSW, Australia.
Wendy A GoldKids Neuroscience Centre, Kids Research, Children's Hospital at Westmead, Westmead, NSW, Australia.
Children's Medical Research Institute · AUChildren's Hospital at Westmead · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rett syndrome (RTT) is an X-linked neurodevelopmental disorder, mostly caused by mutations in

Indexed as

brain organoidsdisease modelingiPSCs (induced pluripotent stem cells)neurodevelopmental disordersRett syndrome

Identifiers

PMID34512241
PMCPMC8423999
OpenAlexW3194193085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.