Evidence map›Paper›PMID 34512227›Full record

ArticleAdvanced functional materials2021

A Broad-Spectrum Antimicrobial and Antiviral Membrane Inactivates SARS-CoV-2 in Minutes.

Qingsheng Liu, Yidan Zhang, Wanjun Liu, Long-Hai Wang, Young W Choi, Megan Fulton, Stephanie Fuchs, Kaavian Shariati, Mingyu Qiao, Victorien Bernat and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Advanced functional materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Lignin: A Sustainable Antiviral Coating Material.ACS sustainable chemistry & engineering · 2022
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Qingsheng LiuDepartment of Biological and Environmental Engineering Cornell University Ithaca NY 14853 USA.
Yidan ZhangDepartment of Fiber Science and Apparel Design Cornell University Ithaca NY 14853 USA.
Wanjun LiuDepartment of Biological and Environmental Engineering Cornell University Ithaca NY 14853 USA.
Long-Hai WangDepartment of Biological and Environmental Engineering Cornell University Ithaca NY 14853 USA.
Young W ChoiBattelle Memorial Institute Columbus OH 43201 USA.
Megan FultonBattelle Memorial Institute Columbus OH 43201 USA.
Stephanie FuchsDepartment of Biological and Environmental Engineering Cornell University Ithaca NY 14853 USA.
Kaavian ShariatiDepartment of Biological and Environmental Engineering Cornell University Ithaca NY 14853 USA.
Mingyu QiaoHalomine Inc. Ithaca NY 14853 USA.
Victorien BernatDepartment of Materials Science and Engineering Cornell University Ithaca NY 14853 USA.
Minglin MaDepartment of Biological and Environmental Engineering Cornell University Ithaca NY 14853 USA.ORCID https://orcid.org/0000-0002-9553-7526
Cornell University · USBattelle · USIthaca College · US

Funding

HaloFilm: a spray-on, re-chargeable, re-applicable antimicrobial coatingR43AI155114 · NIAID · HALOMINE, INC. · PI QIAO, MINGYU · 2020 to 2020
$250k
NIAID NIH HHS R43 AI155114
6 · The paper itself

Abstract

SARS-CoV-2, the virus that caused the COVID-19 pandemic, can remain viable and infectious on surfaces for days, posing a potential risk for fomite transmission. Liquid-based disinfectants, such as chlorine-based ones, have played an indispensable role in decontaminating surfaces but they do not provide prolonged protection from recontamination. Here a safe, inexpensive, and scalable membrane with covalently immobilized chlorine, large surface area, and fast wetting that exhibits long-lasting, exceptional killing efficacy against a broad spectrum of bacteria and viruses is reported. The membrane achieves a more than 6 log reduction within several minutes against all five bacterial strains tested, including gram-positive, gram-negative, and drug-resistant ones as well as a clinical bacterial cocktail. The membrane also efficiently deactivated nonenveloped and enveloped viruses in minutes. In particular, a 5.17 log reduction is achieved against SARS-CoV-2 after only 10 min of contact with the membrane. This membrane may be used on high-touch surfaces in healthcare and other public facilities or in air filters and personal protective equipment to provide continuous protection and minimize transmission risks.

Indexed as

antiviralN‐halamineSARS‐CoV‐2sub‐micron fibrous membraneszwitterion

Identifiers

PMID34512227
PMCPMC8420574
OpenAlexW3194902164

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.