Evidence map›Paper›PMID 34511885›Full record

ArticlePatient preference and adherence2021

The Relationship Between COVID-19 Related Stress and Medication Adherence Among High-Risk Adults During the Acceleration Phase of the US Outbreak.

Caroline Zhao, Stephanie Batio, Rebecca Lovett, Allison P Pack, Michael S Wolf, Stacy C Bailey

Abstract read
In one paragraph

Article in Patient preference and adherence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Caroline ZhaoDivision of General Internal Medicine & Geriatrics, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA.
Stephanie BatioDivision of General Internal Medicine & Geriatrics, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA.
Rebecca LovettDivision of General Internal Medicine & Geriatrics, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA.
Allison P PackDivision of General Internal Medicine & Geriatrics, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA.ORCID 0000-0001-5802-293X
Michael S WolfDivision of General Internal Medicine & Geriatrics, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA.
Stacy C BaileyDivision of General Internal Medicine & Geriatrics, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA.

Funding

Supplement to LitCog III: Health Literacy and Cognitive Function among Older AdultsR01AG030611 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOLF, MICHAEL S · 2007 to 2024
$11.6M
The Claude D. Pepper Older Americans Independence Center (OAIC) at Northwestern UniversityP30AG059988 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ACKERMANN, RONALD T. · 2020 to 2024
$7.1M
Transplant Regimen Adherence for Kidney Recipients by Engaging Information Technologies: The TAKE IT TrialR01DK110172 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LADNER, DANIELA P, WOLF, MICHAEL S · 2017 to 2020
$2.6M
A Universal Medication Schedule to Promote Adherence to Complex Drug RegimensR01AG046352 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BAILEY, STACY C, WOLF, MICHAEL S · 2015 to 2019
$2.5M
NIA NIH HHS P30 AG059988NIA NIH HHS R01 AG030611NIA NIH HHS R01 AG046352NIDDK NIH HHS R01 DK110172
6 · The paper itself

Abstract

purposeTo assess the relationship between stress regarding COVID-19 and medication adherence. PATIENTS AND

methodsOlder adults with ≥1 chronic condition(s) were recruited from 4 active, federally funded studies in Chicago to participate in a longitudinal telephone survey. Participants self-reported stress regarding COVID-19 in the last week. Adherence was measured via the ASK-12 survey.

resultsMost participants reported feeling stressed "some of the time" (54.0%), while 18.2% felt stressed "most" or "all of the time" and 27.8% "never" felt stressed. In bivariate analyses, participants who reported being stressed "most" or "all of the time" had worse medication adherence than participants who reported being stressed "some of the time" or "never" (p < 0.001). In multivariable analyses, participants who reported feeling stressed "most" or "all of the time" had worse adherence than those who "never" felt stressed (Adjusted Least Square Mean (Standard Error): 21.3 (0.6) vs 19.7 (0.6), p=0.01).

conclusionStress due to COVID-19 has significantly impacted medication adherence, which has negative implications for the course of both COVID-19 and comorbid conditions. Healthcare providers should be aware of the potential impact of COVID-19 on patients' mental and physical well-being and consider ways to routinely assess patient experiences.

Indexed as

comorbidityCOVID-19medication adherencestress

Identifiers

PMID34511885
PMCPMC8418366

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.