Evidence map›Paper›PMID 34511565›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Duloxetine-induced Syndrome of Inappropriate Secretion of Antidiuretic Hormone in a Super-elderly Patient.

Toru Hamada, Katsuyuki Matsuki, Seiji Kondou, Shinya Furukawa, Morikazu Onji

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Toru HamadaDepartment of Internal Medicine, National Health Insurance Kuma-Kogen Town Hospital, Japan.
Katsuyuki MatsukiDepartment of Internal Medicine, National Health Insurance Kuma-Kogen Town Hospital, Japan.
Seiji KondouDepartment of Internal Medicine, National Health Insurance Kuma-Kogen Town Hospital, Japan.
Shinya FurukawaHealth Services Center, Ehime University, Japan.
Morikazu OnjiDepartment of Internal Medicine, National Health Insurance Kuma-Kogen Town Hospital, Japan.
Ehime University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Duloxetine is widely used for pain control and depressive syndromes. One of its potential side effects is syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Duloxetine-induced SIADH causes hyponatremia, which leads to a variety of symptoms and has previously been reported in the elderly. In the present case, we experienced a case of the rapid onset of SIADH in a super-elderly woman receiving low-dose duloxetine. Elderly patients tend to have lower duloxetine doses and an earlier onset than non-elderly patients. When hyponatremia occurs after duloxetine administration, duloxetine-induced SIADH should be considered, especially in high-risk elderly patients, regardless of the duloxetine dose or duration of treatment.

Indexed as

HyponatremiaInappropriate ADH SyndromeAgedDuloxetine HydrochlorideFemaleHumansMiddle AgedVasopressinsDuloxetine HydrochlorideVasopressinsduloxetineelderlyhyponatremiasyndrome of inappropriate secretion of antidiuretic hormone (SIADH)

Identifiers

PMID34511565
PMCPMC9038471
OpenAlexW3201547512

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.