Evidence map›Paper›PMID 34511232›Full record

ReviewBest practice & research. Clinical anaesthesiology2021

COVID-19 impact on the renal system: Pathophysiology and clinical outcomes.

Alan D Kaye, Chikezie N Okeagu, Gregory Tortorich, Alex D Pham, Eric I Ly, Kimberley C Brondeel, Matthew R Eng, Markus M Luedi, Richard D Urman, Elyse M Cornett

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Best practice & research. Clinical anaesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Observational
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  9. Article
  10. COVID-19 andInfectious disease reports · 2023
    Article
  11. Article
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  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Alan D KayeDepartments of Anesthesiology and Pharmacology, Toxicology, and Neurosciences, LSU Health Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA. Electronic address: akaye@lsuhsc.edu.
Chikezie N OkeaguDepartment of Anesthesiology, LSU Health Sciences Center, 1542 Tulane Avenue, New Orleans, LA, 70112, USA. Electronic address: cokeag@lsuhsc.edu.
Gregory TortorichLSUHSC New Orleans, New Orleans, LA, USA. Electronic address: gtort1@lsuhsc.edu.
Alex D PhamDepartment of Anesthesiology, LSU Health New Orleans, 1542 Tulane Ave, Room 659, New Orleans, LA, 70112, USA. Electronic address: apham5@lsuhsc.edu.
Eric I LyUniversity of Tennessee Health Science Center College of Medicine, 910 Madison Avenue, Memphis, TN, 38103, USA. Electronic address: ely@uthsc.edu.
Kimberley C BrondeelSchool of Medicine, University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555, USA. Electronic address: kcbronde@utmb.edu.
Matthew R EngDepartment of Anesthesiology, LSU Health Sciences Center, 1542 Tulane Avenue, New Orleans, LA, 70112, USA. Electronic address: meng@lsuhsc.edu.
Markus M LuediBern University Hospital Inselspital, University of Bern, Bern, Switzerland. Electronic address: markus.luedi2@insel.ch.
Richard D UrmanDepartment of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Brigham and Women's Hospital, 75 Francis St, Boston, MA, 02115, USA. Electronic address: rurman@bwh.harvard.edu.
Elyse M CornettDepartment of Anesthesiology, LSU Health Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA. Electronic address: ecorne@lsuhsc.edu.
Louisiana State University Health Sciences Center New Orleans · USLouisiana State University Health Sciences Center Shreveport · USBrigham and Women's Hospital · USThe University of Texas Medical Branch at Galveston · USUniversity of Bern · CHUniversity of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease (COVID-19) causes many deleterious effects throughout the body. Prior studies show that the incidence of acute kidney injury in COVID-19 patients could be as high as 25%. There are also autopsy reports showing evidence of viral tropism to the renal system. In this regard, COVID-19 can damage the kidneys and increase a patient's risk of requiring dialysis. Available evidence suggests that renal involvement in COVID-19 infection is not uncommon, and there has been an increased incidence of chronic kidney disease related to the pandemic. In this literature analysis, we address COVID-19 and its effects on the renal system, including the pathophysiologic mechanisms. We also address current studies on the causes of injury to the renal system, the cause of kidney failure, its effect on mortality, the impact on dialysis patients, and the impact on renal transplant patients. COVID-19 disease may have unique features in individuals on chronic dialysis and kidney transplant recipients, requiring increased vigilance in limiting viral transmission in perioperative, in-patient, and dialysis center settings.

Indexed as

COVID-19HumansKidneyKidney DiseasesRenal DialysisTreatment OutcomecoronavirusCOVID-19dialysisinjurykidneyoutcomesrenal

Identifiers

PMID34511232
PMCPMC7920815
OpenAlexW3134279070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.