Evidence map›Paper›PMID 34511196›Full record

ReviewSurgical oncology clinics of North America2021

Inherited Pancreatic Cancer Syndromes and High-Risk Screening.

Leah H Biller, Brian M Wolpin, Michael Goggins

Open access · greenAbstract readReview
In one paragraph

Review in Surgical oncology clinics of North America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Systemic treatment for advanced pancreatic cancer.World journal of gastrointestinal oncology · 2023
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Familial Pancreatic Cancer.Gastroenterology clinics of North America · 2022
    Review
  10. The Emerging Role of EVA1A in Different Types of Cancers.International journal of molecular sciences · 2022
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Leah H BillerDepartment of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Avenue, Boston, MA, USA. Electronic address: https://twitter.com/leahbillermd.
Brian M WolpinDepartment of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Avenue, Boston, MA, USA. Electronic address: brian_wolpin@dfci.harvard.edu.
Michael GogginsJohns Hopkins University, 1550 Orleans Street, Baltimore, MD, USA. Electronic address: mgoggins@jhmi.edu.
Dana-Farber Cancer Institute · USJohns Hopkins University · USTwitter (United States) · US

Funding

Tumor Antigens for Individual Signatures and TherapyP50CA062924 · NCI · JOHNS HOPKINS UNIVERSITY · PI JAFFEE, ELIZABETH M. · 1993 to 2022
$54.6M
Tissue and Pathology ResourcesP50CA127003 · NCI · DANA-FARBER CANCER INST · PI BASS, ADAM JOEL · 2007 to 2023
$33.2M
Using markers to improve pancreatic cancer screening and surveillance: a multi-center studyU01CA210170 · NCI · JOHNS HOPKINS UNIVERSITY · PI Michael G. Goggins · 2016 to 2026
$9.3M
Circulating Biomarker Consortium for Pancreatic Cancer Early DetectionU01CA210171 · NCI · DANA-FARBER CANCER INST · PI Michael H. Rosenthal, Brian Matthew Wolpin · 2016 to 2026
$8.7M
Using Markers to Improve Pancreatic Cancer ScreeningR01CA176828 · NCI · JOHNS HOPKINS UNIVERSITY · PI GOGGINS, MICHAEL G. · 2013 to 2024
$4.1M
NCI NIH HHS P50 CA062924NCI NIH HHS P50 CA127003NCI NIH HHS R01 CA176828NCI NIH HHS U01 CA210170NCI NIH HHS U01 CA210171
6 · The paper itself

Abstract

Pancreatic cancer is the third leading cause of cancer death in the United States, with a 5-year survival rate of 9%. Individuals with inherited pancreatic cancer syndromes are at an increased risk for developing pancreatic cancer and may benefit from pancreatic cancer surveillance with the goal to detect and intervene on early-stage cancer or high-risk precursor lesions. Given the screening implications for family members and therapeutic implications for probands, all patients diagnosed with pancreatic cancer are recommended to undergo germline genetic testing.

Indexed as

Neoplastic Syndromes, HereditaryPancreatic NeoplasmsEarly Detection of CancerGenetic Predisposition to DiseaseHumansPancreasRisk FactorsUnited StatesCancer riskHereditaryPancreatic cystSurveillance

Identifiers

PMID34511196
PMCPMC8438225
OpenAlexW3199540488

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.