Evidence map›Paper›PMID 34511086›Full record

ArticleBMC musculoskeletal disorders2021

Older fusion-surgery age in congenital scoliosis patients is a risk factor for extended length of stay, more estimated blood loss, longer fused segments and higher medical costs: a retrospective study.

Xiran Chai, Guanfeng Lin, Shengru Wang, Yang Yang, Zhe Su, You Du, Xiaolin Xu, Xiaohan Ye, Jianxiong Shen, Jianguo Zhang

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xiran ChaiDepartments of Orthopaedic Surgery, Peking Union Medical College Hospital (PUMCH), 1st Shuai Fu Yuan Hutong, Dongcheng District, 100730, Beijing, People's Republic of China.
Guanfeng LinDepartments of Orthopaedic Surgery, Peking Union Medical College Hospital (PUMCH), 1st Shuai Fu Yuan Hutong, Dongcheng District, 100730, Beijing, People's Republic of China.
Shengru WangDepartments of Orthopaedic Surgery, Peking Union Medical College Hospital (PUMCH), 1st Shuai Fu Yuan Hutong, Dongcheng District, 100730, Beijing, People's Republic of China.
Yang YangDepartments of Orthopaedic Surgery, Peking Union Medical College Hospital (PUMCH), 1st Shuai Fu Yuan Hutong, Dongcheng District, 100730, Beijing, People's Republic of China.
Zhe SuDepartments of Orthopaedic Surgery, Peking Union Medical College Hospital (PUMCH), 1st Shuai Fu Yuan Hutong, Dongcheng District, 100730, Beijing, People's Republic of China.
You DuDepartments of Orthopaedic Surgery, Peking Union Medical College Hospital (PUMCH), 1st Shuai Fu Yuan Hutong, Dongcheng District, 100730, Beijing, People's Republic of China.
Xiaolin XuDepartments of Orthopaedic Surgery, Peking Union Medical College Hospital (PUMCH), 1st Shuai Fu Yuan Hutong, Dongcheng District, 100730, Beijing, People's Republic of China.
Xiaohan YeDepartments of Orthopaedic Surgery, Peking Union Medical College Hospital (PUMCH), 1st Shuai Fu Yuan Hutong, Dongcheng District, 100730, Beijing, People's Republic of China.
Jianxiong ShenDepartments of Orthopaedic Surgery, Peking Union Medical College Hospital (PUMCH), 1st Shuai Fu Yuan Hutong, Dongcheng District, 100730, Beijing, People's Republic of China.
Jianguo ZhangDepartments of Orthopaedic Surgery, Peking Union Medical College Hospital (PUMCH), 1st Shuai Fu Yuan Hutong, Dongcheng District, 100730, Beijing, People's Republic of China. jgzhang_pumch@yahoo.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNPeking Union Medical College Hospital · CN

Funding

Central University Basic Research Fund of China 3332019021China Postdoctoral Science Foundation 2020M670008ZXNational Key Research and Development Program of China 2017YFC1104902National Natural Science Foundation of China 81902178National Natural Science Foundation of China 81972037Natural Science Foundation of Beijing Municipality L192015
6 · The paper itself

Abstract

backgroundContradictory opinions about whether early correction and fusion surgeries should be performed for congenital scoliosis (CS) patients at a young age exist. The objectives of this study were to analyze the association between patient characteristics and fusion-surgery outcomes in CS patients treated with spinal correction and fusion surgeries and to report risk factors for extended length of stay (LOS), more estimated blood loss (EBL), longer fused segments and higher medical costs.

methodsWe analyzed data of 1,207 CS inpatients treated with fusion surgeries in our institute from January 2010 - December 2019. All patients underwent spinal X-ray, CT, MRI, echocardiogram and urogenital ultrasound. We analyzed demographic and clinical information and outcome measures, including LOS, EBL, fused segments and medical costs.

resultsAge at fusion (OR = 1.053; p < 0.001), musculoskeletal defects (OR = 1.670; p = 0.004) and thoracic deformity (OR = 1.519; p = 0.03) were risk factors for extended LOS. Age at fusion (OR = 1.117; p < 0.001), male sex (OR = 1.813; p < 0.001), mixed defects (OR = 1.662; p = 0.027) and failure of formation (OR = 1.718; p = 0.021) were risk factors for more EBL. Age at fusion (OR = 1.213; p < 0.001) was a risk factor for longer fused segments. Age at fusion (OR = 1.091; p < 0.001) and thoracic deformity (OR = 1.853; p = 0.004) were risk factors for higher medical costs.

conclusionsWe found that older age at fusion in CS patients is a risk factor for extended LOS, more EBL, longer fused segments and higher medical costs with the risk increasing by 5-21 % for each year of age. Other identified risk factors include thoracic deformity for extended LOS; longer fused segments, higher medical costs, and musculoskeletal defects for extended LOS; and CS type (FF and MD) and sex (male) for more EBL.

Indexed as

ScoliosisSpinal FusionAgedHumansLength of StayMaleRetrospective StudiesRisk FactorsTreatment OutcomeCongenital scoliosisEstimated blood lossLength of stayMedical costsRisk factor for fusion surgery

Identifiers

PMID34511086
PMCPMC8436475
OpenAlexW3200834950

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.