Evidence map›Paper›PMID 34510958›Full record

Observational studyThe Journal of international medical research2021

Predictors of acute kidney injury in patients with acute decompensated heart failure in emergency departments in China.

Hongxia Ge, Yang Liang, Yingying Fang, Yi Jin, Wenting Su, Guoqiang Zhang, Jing Wang, Hui Xiong, Deya Shang, Yanfen Chai and 9 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 13 institutions in 1 country.

Hongxia GeEmergency Department, Peking University Third Hospital, No. 49 North Garden Road, Hai-dian District, Beijing, China.
Yang LiangEmergency Department, Peking University Third Hospital, No. 49 North Garden Road, Hai-dian District, Beijing, China.ORCID https://orcid.org/0000-0002-4666-9653
Yingying FangEmergency Department, Peking University Third Hospital, No. 49 North Garden Road, Hai-dian District, Beijing, China.
Yi JinEmergency Department, Peking University Third Hospital, No. 49 North Garden Road, Hai-dian District, Beijing, China.
Wenting SuEmergency Department, Peking University Third Hospital, No. 49 North Garden Road, Hai-dian District, Beijing, China.
Guoqiang ZhangEmergency Department, China-Japan Friendship Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-1728-3847
Jing WangEmergency Department, Xuanwu Hospital Capital Medical University, Beijing, China.
Hui XiongEmergency Department, Peking University First Hospital, Beijing, China.
Deya ShangEmergency Department, Shandong Provincial Hospital, Jinan, Shandong, China.
Yanfen ChaiEmergency Department, Tianjin Medical University General Hospital, Tianjin, China.
Zhi LiuEmergency Department, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Hongyan WeiEmergency Department, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Hairong WangEmergency Department, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Wei ZhangEmergency Department, Tianjin Third Central Hospital, Tianjin, China.
Fei MaEmergency Department, Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China.
Wei ZhaoEmergency Department, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi, China.
Li SunEmergency Department, Shanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Huan HuangEmergency Department, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Qingbian MaEmergency Department, Peking University Third Hospital, No. 49 North Garden Road, Hai-dian District, Beijing, China.
Peking University · CNCapital Medical University · CNChina-Japan Friendship Hospital · CNFirst Hospital of China Medical University · CNGuangdong Provincial People's Hospital · CNQingdao University · CNShandong Provincial Hospital · CNShanxi Medical University · CNSun Yat-sen University · CNTianjin Medical University General Hospital · CNTianjin Third Central Hospital · CNXijing Hospital · CNXinHua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis retrospective multicentre observational study was performed to assess the predictors of acute kidney injury (AKI) in patients with acute decompensated heart failure (ADHF) in emergency departments in China.

methodsIn total, 1743 consecutive patients with ADHF were recruited from August 2017 to January 2018. Clinical characteristics and outcomes were compared between patients with and without AKI. Predictors of AKI occurrence and underdiagnosis were assessed in multivariate regression analyses.

resultsOf the 1743 patients, 593 (34.0%) had AKI. AKI was partly associated with short-term all-cause mortality and cost. Cardiovascular comorbidities such as coronary heart disease, diabetes mellitus, and hypertension remained significant predictors of AKI in the univariate analysis. AKI was significantly more likely to occur in patients with a lower arterial pH, lower albumin concentration, higher creatinine concentration, and higher N-terminal pro-brain natriuretic peptide (NT-proBNP) concentration. Patients treated with inotropic agents were significantly more likely to develop AKI during their hospital stay.

conclusionThis study suggests that cardiovascular comorbidities, arterial pH, the albumin concentration, the creatinine concentration, the NT-proBNP concentration, and use of inotropic agents are predictors of AKI in patients with ADHF.

Indexed as

Acute Kidney InjuryHeart FailureAcute DiseaseBiomarkersEmergency Service, HospitalHumansNatriuretic Peptide, BrainPeptide FragmentsPrognosisRetrospective StudiesBiomarkersNatriuretic Peptide, BrainPeptide Fragmentsacute decompensated heart failureacute kidney injurydiagnosisemergency departmentoutcomesPredictors

Identifiers

PMID34510958
PMCPMC8442502
OpenAlexW3199890795

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.