Evidence map›Paper›PMID 34510824›Full record

ReviewAdvanced healthcare materials2021

The Importance of Interfaces in Multi-Material Biofabricated Tissue Structures.

Martina Viola, Susanna Piluso, Jürgen Groll, Tina Vermonden, Jos Malda, Miguel Castilho

Abstract readReview
In one paragraph

Review in Advanced healthcare materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Martina ViolaDepartment of Orthopeadics, University Medical Center, Heidelberglaan 100, Utrecht, 3508 GA, The Netherlands.
Susanna PilusoDepartment of Orthopeadics, University Medical Center, Heidelberglaan 100, Utrecht, 3508 GA, The Netherlands.
Jürgen GrollDepartment of Functional Materials in Medicine and Dentistry at the Institute of Functional Materials and Biofabrication and Bavarian Polymer Institute, University of Würzburg, Pleicherwall 2, D-97070, Wurzburg, Germany.ORCID 0000-0003-3167-8466
Tina VermondenDepartment of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, 3508 TB, The Netherlands.ORCID 0000-0002-6047-5900
Jos MaldaDepartment of Orthopeadics, University Medical Center, Heidelberglaan 100, Utrecht, 3508 GA, The Netherlands.ORCID 0000-0002-9241-7676
Miguel CastilhoDepartment of Orthopeadics, University Medical Center, Heidelberglaan 100, Utrecht, 3508 GA, The Netherlands.ORCID 0000-0002-4269-5889

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofabrication exploits additive manufacturing techniques for creating 3D structures with a precise geometry that aim to mimic a physiological cellular environment and to develop the growth of native tissues. The most recent approaches of 3D biofabrication integrate multiple technologies into a single biofabrication platform combining different materials within different length scales to achieve improved construct functionality. However, the importance of interfaces between the different material phases, has not been adequately explored. This is known to determine material's interaction and ultimately mechanical and biological performance of biofabricated parts. In this review, this gap is bridged by critically examining the interface between different material phases in (bio)fabricated structures, with a particular focus on how interfacial interactions can compromise or define the mechanical (and biological) properties of the engineered structures. It is believed that the importance of interfacial properties between the different constituents of a composite material, deserves particular attention in its role in modulating the final characteristics of 3D tissue-like structures.

Indexed as

BioprintingPrinting, Three-DimensionalTissue EngineeringTissue Scaffoldsbioinkscompositeshybrid bioprintingmaterials interfacesmultitechnology biofabricationregenerative medicinereinforcement

Identifiers

PMID34510824
PMCPMC11468707

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.