ArticleMolecular and cellular biochemistry2021
Deuterium-depleted water stimulates GLUT4 translocation in the presence of insulin, which leads to decreased blood glucose concentration.
Article in Molecular and cellular biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Unraveling the role of deuterium in cancer: mechanisms, detection techniques, and therapeutic potential.Molecular diversity · 2026Review
- Gene Expression Patterns in Lung Adenocarcinoma Cells in Response to Changes in Deuterium Concentration.International journal of molecular sciences · 2025Article
- Transcriptomic Insights into Late-Life Depression and the Role of Environmental Drinking Water Composition: A Study on 18-Month-Old Mice.International journal of molecular sciences · 2025Article
- Nutritional deuterium depletion and health: a scoping review.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Study of the Effects of Deuterium-Depleted Water on the Expression of GLUT4 and Insulin Resistance in the Muscle Cell Line C2C12.Biomedicines · 2024Article
- The biological impact of deuterium and therapeutic potential of deuterium-depleted water.Frontiers in pharmacology · 2024Review
- Article
- Insulin and the kidneys: a contemporary view on the molecular basis.Frontiers in nephrology · 2023Review
- Deuterium Content of the Organic Compounds in Food Has an Impact on Tumor Growth in Mice.Current issues in molecular biology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Deuterium (D) is a stable isotope of hydrogen (H) with a mass number of 2. It is present in natural waters in the form of HDO, at a concentration of 16.8 mmol/L, equivalent to 150 ppm. In a phase II clinical study, deuterium depletion reduced fasting glucose concentration and insulin resistance. In this study, we tested the effect of subnormal D-concentration on glucose metabolism in a streptozotocin (STZ)-induced diabetic rat model. Animals were randomly distributed into nine groups to test the effect of D
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Registered trials
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