SynthesisJournal of affective disorders2021
Prenatal maternal posttraumatic stress disorder as a risk factor for adverse birth weight and gestational age outcomes: A systematic review and meta-analysis.
Synthesis in Journal of affective disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Associations between PTSD and pregnancy outcomes: systematic review and Meta- analysis.BMC pregnancy and childbirth · 2025Pooled it
- Comparing two posttraumatic stress disorder screening approaches to improve health outcomes in pregnant black women: a comparative effectiveness trial protocol.European journal of psychotraumatology · 2026Trial
- Post-traumatic stress disorder and adverse pregnancy and birth outcomes: a population-based study.European journal of psychotraumatology · 2026Article
- The impact of mental health disorders in pregnancy on obstetric and neonatal outcomes: A narrative review.Brain, behavior, & immunity - health · 2026Review
- Breaking the cycle: a review of the impacts of maternal PTSD, adverse pregnancy outcomes, and health disparities among Black women.Maternal health, neonatology and perinatology · 2026Review
- Closing a critical gap in perinatal mental health: The case for posttraumatic stress disorder screening in obstetric care.Pregnancy (Hoboken, N.J.) · 2026Article
- Brief Narrative Exposure Therapy for Perinatal Trauma: A Case Study.Cognitive and behavioral practice · 2026Article
- Trends and adverse pregnancy outcomes associated with post-traumatic stress disorder: a population-based study of delivery hospitalisations.Archives of gynecology and obstetrics · 2026Article
- Impact of the severity of maternal depression, anxiety, and post-traumatic stress disorder, as well as alcohol consumption, on perinatal outcomes.BMC pregnancy and childbirth · 2026Article
- Post-traumatic stress disorder and adverse pregnancy outcomes: sexual orientation disparities in a prospective cohort study.BMC pregnancy and childbirth · 2026Article
- Estimated Prevalence of Current Posttraumatic Stress Disorder Among Pregnant Women With Opioid Use Disorder-MATernaL and Infant Clinical NetworK (MAT-LINK), 2014-2021.Journal of addiction medicine · 2026Article
- Breaking the Cycle of Preterm Birth: A Prospective Cohort Study on Maternal Stress and Recurrent Preterm Birth.BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Advancing equity in perinatal PTSD: a systemic trauma framework for written exposure therapy.Frontiers in psychiatry · 2026Article
- Article
- Longitudinal effects of pregnancy on PTSD symptoms in black female participants: Moderation by sexual trauma and progesterone.Psychoneuroendocrinology · 2025Article
- The Impact of Lifestyle on Reproductive Health: Microbial Complexity, Hormonal Dysfunction, and Pregnancy Outcomes.International journal of molecular sciences · 2025Review
- Validation of the Polish PPQ-II: sociodemographic and clinical correlates of perinatal PTSD.Frontiers in psychology · 2025Article
- Narrative Exposure Therapy: Expanding Virtual Treatment of Posttraumatic Stress Disorder to the Postpartum Period.Journal of aggression, maltreatment & trauma · 2025Article
- Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach.Developmental cognitive neuroscience · 2025Article
- Associations Among Racial Discrimination, Perceived Stress, and Birth Satisfaction in Black Women in the Postpartum Period.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN · 2024Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAlthough not routinely assessed, prenatal posttraumatic stress disorder (PTSD) is associated with poor maternal mental health and mother-infant bonding. Prenatal PTSD may also be associated with birth weight and gestational age outcomes, but this remains unclear. This systematic review and meta-analysis investigated the association of prenatal PTSD with risk of low birth weight (LBW) or preterm birth (PTB) (dichotomous medically-defined cut-offs) or with birth weight (BW) or gestational age (GA) (continuous variables).
methodsA comprehensive literature search was conducted in Web of Science, MedLine, PubMed, and PsychInfo. Data were collected and processed according to Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines. Study quality was assessed with the Newcastle-Ottowa Quality Assessment Scale. Pooled effect sizes were estimated with random-effects models (correlation for continuous and odds ratios for dichotomous outcomes).
resultsSixteen studies with 51,470 participants (prenatal PTSD 8%) were included in 4 meta-analyses. Maternal prenatal PTSD was associated with higher risks of LBW (OR = 1.96; 95% CI, 1.26, 3.03; P = .003), PTB (OR = 1.42; 95% CI, 1.16, 1.73; P = .001), and reduced GA (r = -0.04; 95% CI, -0.06, -0.01; P = .002). LIMITATIONS: Different designs across studies, variety of PTSD assessment practices, and a small pool of studies were noted.
conclusionsFindings suggest prenatal PTSD presents increased risks of LBW, PTB, and reduced GA. Evidence of physical harm to neonates from prenatal PTSD provides a powerful rationale to increase prenatal PTSD screening and identify effective prenatal interventions to improve maternal and child outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.