Evidence map›Paper›PMID 34508758›Full record

ArticleJournal of theoretical biology2021

Network models to evaluate vaccine strategies towards herd immunity in COVID-19.

Josephine N A Tetteh, Van Kinh Nguyen, Esteban A Hernandez-Vargas

Abstract read
In one paragraph

Article in Journal of theoretical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Impulsive Neural Control to Schedule Antivirals and Immunomodulators for COVID-19.Proceedings of the ... IEEE Conference on Decision & Control. IEEE Conference on Decision & Control · 2022
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  16. Nonlinear time-series forecasts for decision support: short-term demand for ICU beds in Santiago, Chile, during the 2021 COVID-19 pandemic.International transactions in operational research : a journal of The International Federation of Operational Research Societies · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Josephine N A TettehFrankfurt Institute for Advanced Studies, Frankfurt am Main, Germany; Institut für Mathematik, Goethe-Universität, Frankfurt am Main, Germany.
Van Kinh NguyenImperial College London, London, United Kingdom.
Esteban A Hernandez-VargasFrankfurt Institute for Advanced Studies, Frankfurt am Main, Germany; Instituto de Matemáticas, Universidad Nacional Autonoma de Mexico, Boulevard Juriquilla 3001, Santiago de Querétaro, Qro. 76230, Mexico. Electronic address: esteban@im.unam.mx.

Funding

Medical Research Council MC_PC_19012Medical Research Council MR/R015600/1
6 · The paper itself

Abstract

Vaccination remains a critical element in the eventual solution to the COVID-19 public health crisis. Many vaccines are already being mass produced and supplied in many countries. However, the COVID-19 vaccination programme will be the biggest in history. Reaching herd immunity will require an unprecedented mass immunisation campaign that will take several months and millions of dollars. Using different network models, COVID-19 pandemic dynamics of different countries can be recapitulated such as in Italy. Stochastic computational simulations highlight that peak epidemic sizes in a population strongly depend on the network structure. Assuming a vaccine efficacy of at least 80% in a mass vaccination program, at least 70% of a given population should be vaccinated to obtain herd immunity, independently of the network structure. If the vaccine efficacy reports lower levels of efficacy in practice, then the coverage of vaccination would be needed to be even higher. Simulations suggest that the "Ring of Vaccination" strategy, vaccinating susceptible contact and contact of contacts, would prevent new waves of COVID -19 meanwhile a high percent of the population is vaccinated.

Indexed as

COVID-19VaccinesCOVID-19 VaccinesHumansImmunity, HerdMass VaccinationPandemicsSARS-CoV-2VaccinationCOVID-19 VaccinesVaccinesCOVID-19EpidemicsMass vaccinationNetworksRing of VaccinationSARS-CoV-2Vaccination

Identifiers

PMID34508758
PMCPMC8426151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.