Evidence map›Paper›PMID 34508256›Full record

ArticleEuropean journal of clinical nutrition2022

Placental expression of RNU44, RNU48 and miR-16-5p: stability and relations with fetoplacental growth.

P Kochhar, P Dwarkanath, G Ravikumar, A Thomas, J Crasta, T Thomas, A V Kurpad, A Mukhopadhyay

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Article in European journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

P KochharDivision of Nutrition, St. John's Research Institute, A recognized research centre of University of Mysore, Bangalore, Karnataka, India.
P DwarkanathDivision of Nutrition, St. John's Research Institute, A recognized research centre of University of Mysore, Bangalore, Karnataka, India.ORCID http://orcid.org/0000-0002-9843-1057
G RavikumarDepartment of Pathology, St John's Medical College Hospital, Bangalore, Karnataka, India.ORCID http://orcid.org/0000-0002-4426-6914
A ThomasDepartment of Obstetrics and Gynaecology, St John's Medical College Hospital, Bangalore, Karnataka, India.
J CrastaDepartment of Pathology, St John's Medical College Hospital, Bangalore, Karnataka, India.
T ThomasDepartment of Biostatistics, St. John's Medical College Hospital, Bangalore, Karnataka, India.ORCID http://orcid.org/0000-0002-1786-6076
A V KurpadDivision of Nutrition, St. John's Research Institute, A recognized research centre of University of Mysore, Bangalore, Karnataka, India.ORCID http://orcid.org/0000-0001-7998-2438
A MukhopadhyayDivision of Nutrition, St. John's Research Institute, A recognized research centre of University of Mysore, Bangalore, Karnataka, India. arpitam@sjri.res.in.ORCID http://orcid.org/0000-0001-8260-5385
St.John's Medical College Hospital · INUniversity of Mysore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe current study aimed to identify suitable reference miRNA for placental miRNA expression analysis in a set of well-characterized and fetal-sex balanced small- (SGA) and appropriate- (AGA) for gestational age full-term singleton pregnancies. SUBJECTS/

methodsIn this retrospective study, placental samples (n = 106) from 35 SGA (19 male and 16 female) and 71 AGA (30 male and 41 female) full-term singleton pregnancies were utilized. Placental transcript abundance of three widely used reference miRNAs [miR-16-5p and Small nucleolar RNAs (snoRNAs) RNU44 and RNU48] were assessed by real-time quantitative PCR. Raw cycle threshold (C

resultsRaw C

conclusionWe recommend miR-16-5p and RNU44 as suitable reference miRNAs for placental samples from settings similar to our study.

Indexed as

Infant, Small for Gestational AgeMicroRNAsPlacentaRNA, Small NucleolarFemaleGestational AgeHumansInfant, NewbornMalePregnancyRetrospective StudiesMicroRNAsMIRN16 microRNA, humanRNA, Small Nucleolar

Identifiers

PMID34508256
OpenAlexW3196664312

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.