Evidence map›Paper›PMID 34508103›Full record

ArticleNPJ breast cancer2021

Circadian PERformance in breast cancer: a germline and somatic genetic study of PER3

Jaume Fores-Martos, Raimundo Cervera-Vidal, Julia Sierra-Roca, Carlos Lozano-Asencio, Vita Fedele, Sten Cornelissen, Hege Edvarsen, Irene Tadeo-Cervera, Pilar Eroles, Ana Lluch and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ breast cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Biological clock regulation by theFrontiers in cell and developmental biology · 2024
    Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 5 countries.

Jaume Fores-MartosESI International Chair at CEU-UCH, CEU Universities, Valencia, Spain.
Raimundo Cervera-VidalINCLIVA Research Institute. Hospital Clínico Universitario de Valencia, Valencia, Spain.
Julia Sierra-RocaServicio de Pediatria, Hospital La Fe, Valencia, Spain.
Carlos Lozano-AsencioINCLIVA Research Institute. Hospital Clínico Universitario de Valencia, Valencia, Spain.ORCID http://orcid.org/0000-0001-5045-3401
Vita FedeleDigestive Molecular Clinical Oncology Research Unit, Section of Medical Oncology, Department of Medicine, University of Verona, Verona, Italy.
Sten CornelissenDivision of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Hege EdvarsenDepartment of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway.
Irene Tadeo-CerveraDepartamento de Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos. Facultad de Veterinaria, Universidad CEU Cardenal Herrera. CEU Universities, Valencia, Spain.ORCID http://orcid.org/0000-0003-3690-5007
Pilar ErolesINCLIVA Research Institute. Hospital Clínico Universitario de Valencia, Valencia, Spain.
Ana LluchINCLIVA Research Institute. Hospital Clínico Universitario de Valencia, Valencia, Spain.
Rafa Tabares-SeisdedosBiomedical Research Networking Center of Mental Health (CIBERSAM), Madrid, Spain.
Antonio FalcóESI International Chair at CEU-UCH, CEU Universities, Valencia, Spain.ORCID http://orcid.org/0000-0001-6225-0935
Laura J Van't VeerUCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-9838-8298
Marjanka SchmidtDepartamento de Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos. Facultad de Veterinaria, Universidad CEU Cardenal Herrera. CEU Universities, Valencia, Spain.ORCID http://orcid.org/0000-0002-2228-429X
David A QuigleyUCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
Anne-Lise Børresen-DaleDepartment of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway.
Vessela N KristensenDepartment of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway.
Allan BalmainUCSF Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
Joan ClimentESI International Chair at CEU-UCH, CEU Universities, Valencia, Spain. joan.climentbataller@uchceu.es.ORCID http://orcid.org/0000-0002-8927-6614
Hospital Clínico Universitario de Valencia · ESOslo University Hospital · NOUniversidad Cardenal Herrera CEU · ESUniversity of California, San Francisco · USThe Netherlands Cancer Institute · NLUniversidad San Pablo CEU · ESUniversitat de València · ESUniversity of Verona · ITValencian International University · ES

Funding

Systems genetics analysis of tumor evolution in the mouseR35CA210018 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ALLAN BALMAIN · 2017 to 2026
$8.0M
Ministry of Economy and Competitiveness | Instituto de Salud Carlos III (Institute of Health Carlos III) PI13/01887Ministry of Economy and Competitiveness | Instituto de Salud Carlos III (Institute of Health Carlos III) PI16/00393NCI NIH HHS R35 CA210018
6 · The paper itself

Abstract

Polymorphisms in the PER3 gene have been associated with several human disease phenotypes, including sleep disorders and cancer. In particular, the long allele of a variable number of tandem repeat (VNTR) polymorphism has been previously linked to an increased risk of breast cancer. Here we carried out a combined germline and somatic genetic analysis of the role of the PER3

Identifiers

PMID34508103
PMCPMC8433453
OpenAlexW3197041067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.