Evidence map›Paper›PMID 34508077›Full record

ArticleNature communications2021

Trade-offs between individual and ensemble forecasts of an emerging infectious disease.

Rachel J Oidtman, Elisa Omodei, Moritz U G Kraemer, Carlos A Castañeda-Orjuela, Erica Cruz-Rivera, Sandra Misnaza-Castrillón, Myriam Patricia Cifuentes, Luz Emilse Rincon, Viviana Cañon, Pedro de Alarcon and 12 more

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Machine learning and probabilistic approaches for forecasting infectious disease transmission and cases.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026
    Article
  4. Article
  5. Article
  6. Coordinating collaborative infectious disease modeling projects with the hubverse.medRxiv : the preprint server for health sciences · 2025
    Article
  7. Ensemble approaches for short-term dengue fever forecasts: A global evaluation study.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Modeling zoonotic and vector-borne viruses.Current opinion in virology · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. District-Level Forecast of Achieving Trachoma Elimination as a Public Health Problem By 2030: An Ensemble Modelling Approach.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Rachel J OidtmanDepartment of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, USA. rjoidtman@gmail.com.ORCID http://orcid.org/0000-0003-1773-9533
Elisa OmodeiUNICEF, New York, NY, USA.ORCID http://orcid.org/0000-0002-6748-5124
Moritz U G KraemerDepartment of Zoology, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-8838-7147
Carlos A Castañeda-OrjuelaInstituto Nacional de Salud, Bogotá, Colombia.ORCID http://orcid.org/0000-0002-8735-6223
Erica Cruz-RiveraInstituto Nacional de Salud, Bogotá, Colombia.
Sandra Misnaza-CastrillónInstituto Nacional de Salud, Bogotá, Colombia.
Myriam Patricia CifuentesMinisterio de Salud y Protección Social, Bogotá, Colombia.ORCID http://orcid.org/0000-0002-2302-123X
Luz Emilse RinconMinisterio de Salud y Protección Social, Bogotá, Colombia.
Viviana CañonUNICEF, Bogotá, Colombia.
Pedro de AlarconLUCA Telefonica Data Unit, Madrid, Spain.ORCID http://orcid.org/0000-0001-5137-641X
Guido EspañaDepartment of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, USA.
John H HuberDepartment of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, USA.
Sarah C HillDepartment of Zoology, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-2995-2596
Christopher M BarkerDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicince, University of California, Davis, CA, USA.ORCID http://orcid.org/0000-0002-7941-346X
Michael A JohanssonDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.ORCID http://orcid.org/0000-0002-5090-7722
Carrie A ManoreInformation Systems and Modeling (A-1), Los Alamos National Laboratory, Los Alamos, NM, USA.
Robert C ReinerInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-1056-7919
Isabel Rodriguez-BarraquerDepartment of Medicine, University of California, San Francisco, CA, USA.
Amir S SirajDepartment of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, USA.
Enrique Frias-MartinezTelefonica Research, Madrid, Spain.ORCID http://orcid.org/0000-0001-5348-3120
Manuel García-HerranzUNICEF, New York, NY, USA. mgarciaherranz@unicef.org.ORCID http://orcid.org/0000-0002-4252-4975
T Alex PerkinsDepartment of Biological Sciences and Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, USA. taperkins@nd.edu.ORCID http://orcid.org/0000-0002-7518-4014

Funding

Wellcome TrustWellcome Trust 220414/Z/20/Z
6 · The paper itself

Abstract

Probabilistic forecasts play an indispensable role in answering questions about the spread of newly emerged pathogens. However, uncertainties about the epidemiology of emerging pathogens can make it difficult to choose among alternative model structures and assumptions. To assess the potential for uncertainties about emerging pathogens to affect forecasts of their spread, we evaluated the performance 16 forecasting models in the context of the 2015-2016 Zika epidemic in Colombia. Each model featured a different combination of assumptions about human mobility, spatiotemporal variation in transmission potential, and the number of virus introductions. We found that which model assumptions had the most ensemble weight changed through time. We additionally identified a trade-off whereby some individual models outperformed ensemble models early in the epidemic, but on average the ensembles outperformed all individual models. Our results suggest that multiple models spanning uncertainty across alternative assumptions are necessary to obtain robust forecasts for emerging infectious diseases.

Indexed as

Epidemiological MonitoringColombiaCommunicable Diseases, EmergingData Interpretation, StatisticalDatasets as TopicEpidemicsForecastingHumansModels, StatisticalSpatio-Temporal AnalysisUncertaintyZika Virus Infection

Identifiers

PMID34508077
PMCPMC8433472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.