Evidence map›Paper›PMID 34507991›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Local thermodynamics govern formation and dissolution of

Anatol W Fritsch, Andrés F Diaz-Delgadillo, Omar Adame-Arana, Carsten Hoege, Matthäus Mittasch, Moritz Kreysing, Mark Leaver, Anthony A Hyman, Frank Jülicher, Christoph A Weber

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Distinguishing near- versus off-critical phase behaviors of intrinsically disordered proteins.Reports on progress in physics. Physical Society (Great Britain) · 2026
    Article
  5. Article
  6. Article
  7. Diverse, distinct, and densely packed DNA nanostar droplets.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anatol W FritschMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.ORCID 0000-0003-0986-7068
Andrés F Diaz-DelgadilloMax Planck Institute for Evolutionary Biology, 24306 Plön, Germany.ORCID 0000-0003-0168-1840
Omar Adame-AranaDivision Biological Physics, Max Planck Institute for the Physics of Complex Systems, 01187 Dresden, Germany.ORCID 0000-0001-5828-0584
Carsten HoegeMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Matthäus MittaschMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Moritz KreysingMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.ORCID 0000-0001-7432-3871
Mark LeaverMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.ORCID 0000-0003-2796-4312
Anthony A HymanMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Frank JülicherDivision Biological Physics, Max Planck Institute for the Physics of Complex Systems, 01187 Dresden, Germany.ORCID 0000-0003-4731-9185
Christoph A WeberDivision Biological Physics, Max Planck Institute for the Physics of Complex Systems, 01187 Dresden, Germany; christoph.weber@physik.uni-augsburg.de.ORCID 0000-0001-6279-0405

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Membraneless compartments, also known as condensates, provide chemically distinct environments and thus spatially organize the cell. A well-studied example of condensates is P granules in the roundworm

Indexed as

AnimalsBiomolecular CondensatesCaenorhabditis elegansCaenorhabditis elegans ProteinsEntropyGerm Cell Ribonucleoprotein GranulesGerm CellsSolubilityTemperatureThermodynamicsCaenorhabditis elegans Proteinsin vivo phase diagramP granulesphase separationtemperature

Identifiers

PMID34507991
PMCPMC8449359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.