Evidence map›Paper›PMID 34507601›Full record

ArticleCritical care (London, England)2021

Between-centre differences in care for in-hospital cardiac arrest: a prospective cohort study.

B Y Gravesteijn, M Schluep, H F Lingsma, R J Stolker, H Endeman, S E Hoeks, ROUTINE-study consortium

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

B Y GravesteijnDepartment of Public Health, Erasmus University Medical Center, Postbus, 3000 CA, Rotterdam, The Netherlands. b.gravesteijn@erasmusmc.nl.ORCID 0000-0001-8096-5803
M SchluepDepartment of Anesthesiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
H F LingsmaDepartment of Public Health, Erasmus University Medical Center, Postbus, 3000 CA, Rotterdam, The Netherlands.
R J StolkerDepartment of Anesthesiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
H EndemanDepartment of Intensive Care, Erasmus University Medical Center, Rotterdam, The Netherlands.
S E HoeksDepartment of Anesthesiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
ROUTINE-study consortium
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurvival after in-hospital cardiac arrest is poor, but current literature shows substantial heterogeneity in reported survival rates. This study aims to evaluate care for patients suffering in-hospital cardiac arrest (IHCA) in the Netherlands by assessing between-hospital heterogeneity in outcomes and to explain this heterogeneity stemming from differences in case-mix or differences in quality of care.

methodsA prospective multicentre study was conducted comprising 14 centres. All IHCA patients were included. The adjusted variation in structure and process indicators of quality of care and outcomes (in-hospital mortality and cerebral performance category [CPC] scale) was assessed with mixed effects regression with centre as random intercept. Variation was quantified using the median odds ratio (MOR), representing the expected odds ratio for poor outcome between two randomly picked centres.

resultsAfter excluding centres with less than 10 inclusions (2 centres), 701 patients were included of whom, 218 (32%) survived to hospital discharge. The unadjusted and case-mix adjusted MOR for mortality was 1.19 and 1.05, respectively. The unadjusted and adjusted MOR for CPC score was 1.24 and 1.19, respectively. In hospitals where personnel received cardiopulmonary resuscitation (CPR) training twice per year, 183 (64.7%) versus 290 (71.4%) patients died or were in a vegetative state, and 59 (20.8%) versus 68 (16.7%) patients showed full recovery (p < 0.001).

conclusionIn the Netherlands, survival after IHCA is relatively high and between-centre differences in outcomes are small. The existing differences in survival are mainly attributable to differences in case-mix. Variation in neurological outcome is less attributable to case-mix.

Indexed as

AgedCohort StudiesFemaleHeart ArrestHospital MortalityHospitalsHumansMaleMiddle AgedNetherlandsOutcome Assessment, Health CareProspective StudiesBetween-centre differencesCardiopulmonary resuscitationCohort studyIn-hospital cardiac arrestQuality of care

Identifiers

PMID34507601
PMCPMC8431928
OpenAlexW3198056666

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.