ArticleCritical care (London, England)2021
The management of multi-morbidity in elderly patients: Ready yet for precision medicine in intensive care?
Article in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07001410 (Geriatrics in the Intensive Care Unit. An Observational Clinical Trial), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Geriatrics in the Intensive Care Unit. An Observational Clinical Trial
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Person-centred care models for institutionalised older adults requiring palliative care: an integrative review.BMC geriatrics · 2026Pooled it
- Prevalence and representation of comorbidities and multimorbidity in randomised controlled trials in sepsis or septic shock: a systematic review.Critical care (London, England) · 2026Pooled it
- Age and Sex Matter: Phenotypic Heterogeneity, Diagnostic Gaps, and Screening Tool Performance in Obstructive Sleep Apnea-A 10-Year Sleep Clinic Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Proposing a novel ABCDEF framework for managing critical illness in geriatrics: challenges and perspectives.Annals of medicine · 2025Article
- Association between serum potassium and 28-day mortality in elderly patients with sepsis: a multicenter cohort study.BMC geriatrics · 2025Article
- Impact of comorbidities on management and outcomes of patients weaning from invasive mechanical ventilation: insights from the WEAN SAFE study.Critical care (London, England) · 2025Article
- Challenges in Obstructive Sleep Apnea Management in Elderly Patients.Journal of clinical medicine · 2024Review
- Prognosticating the outcome of intensive care in older patients-a narrative review.Annals of intensive care · 2024Review
- Critical care beyond organ support: the importance of geriatric rehabilitation.Annals of intensive care · 2024Review
- Acute Gastrointestinal Injury in Polytrauma: Special Attention to Elderly Patients.International journal of medical sciences · 2024Observational
- Limiting life-sustaining treatment for very old ICU patients: cultural challenges and diverse practices.Annals of intensive care · 2023Article
- Baseline Serum Biomarkers Predict Response to a Weight Loss Intervention in Older Adults with Obesity: A Pilot Study.Metabolites · 2023Article
- The role of clinical phenotypes in decisions to limit life-sustaining treatment for very old patients in the ICU.Annals of intensive care · 2023Article
- Sex Differences in Multimorbidity, Inappropriate Medication and Adverse Outcomes of Inpatient Care: MoPIM Cohort Study.International journal of environmental research and public health · 2023Article
- Elderly Patients and Management in Intensive Care Units (ICU): Clinical Challenges.Clinical interventions in aging · 2023Review
- Long-term recovery after critical illness in older adults.Current opinion in critical care · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 9 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is ongoing demographic ageing and increasing longevity of the population, with previously devastating and often-fatal diseases now transformed into chronic conditions. This is turning multi-morbidity into a major challenge in the world of critical care. After many years of research and innovation, mainly in geriatric care, the concept of multi-morbidity now requires fine-tuning to support decision-making for patients along their whole trajectory in healthcare, including in the intensive care unit (ICU). This article will discuss current challenges and present approaches to adapt critical care services to the needs of these patients.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.