Evidence map›Paper›PMID 34507231›Full record

ArticleEnvironment international2021

A self-controlled approach to survival analysis, with application to air pollution and mortality.

Joel D Schwartz, Ma'ayan Yitshak-Sade, Antonella Zanobetti, Qian Di, Weeberb J Requia, Francesca Dominici, Murray A Mittleman

Abstract read
In one paragraph

Article in Environment international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Estimating daily ozone levels in urban ambient air.Environmental monitoring and assessment · 2026
    Article
  4. Long-term exposure to ambient PMEnvironmental epidemiology (Philadelphia, Pa.) · 2025
    Article
  5. Measurement error correction for ambient PMEnvironmental research · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joel D SchwartzHarvard TH Chan School of Public Health, Department of Environmental Health, United States; Harvard TH Chan School of Public Health, Department of Epidemiology, United States. Electronic address: joel@hsph.harvard.edu.
Ma'ayan Yitshak-SadeHarvard TH Chan School of Public Health, Department of Environmental Health, United States.
Antonella ZanobettiHarvard TH Chan School of Public Health, Department of Environmental Health, United States.
Qian DiHarvard TH Chan School of Public Health, Department of Environmental Health, United States.
Weeberb J RequiaHarvard TH Chan School of Public Health, Department of Environmental Health, United States.
Francesca DominiciHarvard TH Chan School of Public Health, Department of Biostatistics, United States.
Murray A MittlemanHarvard TH Chan School of Public Health, Department of Epidemiology, United States.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Metals, Nutrition and Stress in Child DevelopmentP01ES012874 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SCHWARTZ, JOEL D · 2004 to 2008
$3.2M
Identifying low dose measurement error corrected effects of multiple pollutants using causal modelingR01ES032418 · NIEHS · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI SCHWARTZ, JOEL D · 2021 to 2024
$1.7M
NIEHS NIH HHS P01 ES012874NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES032418
6 · The paper itself

Abstract

backgroundMany studies have reported that long-term air pollution exposure is associated with increased mortality rates. These investigations have been criticized for failure to control for omitted, generally personal, confounders. Study designs that are robust to such confounders can address this issue.

methodsWe used a self-controlled design for survival analysis. We stratified on each person in the Medicare cohort between 2000 and 2015 who died, and examined whether PM

resultsThere were 6,452,618 deaths in the study population in the study period. We observed a 5.37% increase in the mortality rate (95% CI 4.67%, 6.08%) for every 5 μg/m

conclusionThere is strong evidence that the association between annual exposure to PM

Indexed as

Air PollutantsAir PollutionAgedEnvironmental ExposureHumansMedicareMortalityNitrogen DioxideParticulate MatterSurvival AnalysisUnited StatesAir PollutantsNitrogen DioxideParticulate MatterAir pollutionMortalityNO2OzoneParticlesSelf-controlledSurvival

Identifiers

PMID34507231
PMCPMC8490318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.