Evidence map›Paper›PMID 34507135›Full record

ArticlePublic health2021

Increasing impact of COVID-19 on young adults: evidence from hospitalisations in Brazil.

R Guimarães, D A M Villela, D R Xavier, R Saldanha, C Barcellos, C M de Freitas, M C Portela

Open access · greenAbstract read
In one paragraph

Article in Public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

R GuimarãesFiocruz COVID-19 Observatory, Oswaldo Cruz Foundation, Brazil.
D A M VillelaFiocruz COVID-19 Observatory, Oswaldo Cruz Foundation, Brazil.
D R XavierFiocruz COVID-19 Observatory, Oswaldo Cruz Foundation, Brazil.
R SaldanhaFiocruz COVID-19 Observatory, Oswaldo Cruz Foundation, Brazil.
C BarcellosFiocruz COVID-19 Observatory, Oswaldo Cruz Foundation, Brazil.
C M de FreitasFiocruz COVID-19 Observatory, Oswaldo Cruz Foundation, Brazil.
M C PortelaFiocruz COVID-19 Observatory, Oswaldo Cruz Foundation, Brazil. Electronic address: mportela@ensp.fiocruz.br.
Fundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesConcerns about the increasing impact of severe COVID-19 in younger individuals in Brazil came after a recent synchronised country-wide wave of cases in Brazil. This communication analyses how hospitalisations due to COVID-19 changed in the age groups 18-49 years and ≥70 years. STUDY

designLongitudinal study based on secondary data.

methodsData from SIVEP-Gripe, a public and open-access database of Severe Acute Respiratory Illness records (including COVID-19 notifications), were used in this study. Statistical control charts examined changes in the magnitude and variation of younger (18-49 years) and older (≥70 years) adults who were hospitalised between 15th March 2020 and 19th June 2021.

resultsDuring the few first weeks of the pandemic in Brazil, the number of COVID-19 hospitalisations increased in older adults but decreased in younger adults. Subsequently, hospitalisations reached statistical control zones in epidemiological weeks (EW) 19-48 of 2020 (EW 19-48/2020) and EW 03-05/2021 (18-49 y, mean = 26.1%; ≥70 y, mean = 32.8%). Between EW 49/2020 and EW 02/2021, the number of hospitalisations of younger adults dropped to levels below the lower control limit. In contrast, the number of hospitalisations of older adults surpassed the upper limit of the corresponding statistical control zones. However, from EW 06/2021, numbers of hospitalisations changed from statistical control zones, with hospitalisations of younger adults increasing and reaching 44.9% in EW 24/2021 and hospitalisations of older adults decreasing until EW 19/2021 (14.1%) and reaching 17.3% in EW 24/2021.

conclusionsAn increasing number of COVID-19 hospitalisations were observed in younger adults from EW 06/2021. This could be a result of the successful vaccination programme in older adults, who were initially prioritised, and possibly an increased exposure to highly transmissible variants of COVID-19 in younger adults who had to go to work in the absence of social protection (i.e. government financial support). Potential consequences of COVID-19 hospitalisations in younger adults could include a reduced life expectancy of the population and an increased number of people unable to perform daily activities due to post-COVID-19 conditions.

Indexed as

COVID-19AdolescentAdultAgedBrazilHospitalizationHumansLongitudinal StudiesMiddle AgedSARS-CoV-2Young AdultAge structureBrazilCOVID-19Rejuvenation trend

Identifiers

PMID34507135
PMCPMC8349686
OpenAlexW3189215438

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.